接触哒螨灵致中毒性表皮坏死松解症样系统性接触性皮炎
A case of toxic epidermal necrolysis-like systemic contact dermatitis following exposure to pyridaben insecticide
万勇军 1杨海晶 1严翘 1董正邦 1王飞1
作者信息
- 1. 东南大学附属中大医院皮肤科,江苏 南京 210009
- 折叠
摘要
报告1例中毒性表皮坏死松解症样系统性接触性皮炎.患者男,70岁.全身红斑、水疱及糜烂4周.患者发病前有农药哒螨灵接触史,否认其他用药史.皮肤科检查:面部、躯干及四肢皮肤广泛糜烂,基底红润,呈烫伤样外观,尼氏征阳性,皮损面积约75％.腹部皮损组织病理检查:浅表糜烂,部分表皮缺失,基底层灶性液化变性;真皮上中部小血管管周可见稍密集的以淋巴细胞为主单一核炎性细胞浸润.诊断:中毒性表皮坏死松解症样系统性接触性皮炎.
Abstract
A case of toxic epidermal necrolysis-like systemic contact dermatitis is reported.A 70-year-old male presented with erythema,blisters and erosions all over the body for four weeks.Prior to onset,he reported a history of pyridaben insecticide contact and denied the history of medications.Dermatological examination revealed erosions over the face,trunk,and extrem-ities with a rosy base and scald-like appearance.Nikolsky sign was positive,and 75％of body surface area was affected.Histopatho-logical examination of the abdominal skin lesion showed detachment of partial epidermis,focal liquefaction of basal cells and a slightly dense infiltration of lymphocyte-dominated mononuclear inflammatory cells around the tubules of small blood vessels in the mid-superior dermis.A diagnosis was made as toxic epidermal necrolysis-like systemic contact dermatitis.
关键词
哒螨灵/表皮坏死松解症,中毒性/皮炎,接触性,系统性Key words
pyridaben/toxic epidermal necrolysis/systemic contact dermatitis引用本文复制引用
出版年
2025
NETL
NSTL
万方数据