Clinical features of sixteen-and-a-half syndrome combined with vertical gaze-evoked nystagmus(report of one case)
Objective The purpose of this paper is to further understand the clinical manifestations of impaired vestibular function in the sixteen-and-a-half syndrome and the different forms of nystagmus caused by pontine lesions,so as to improve the clinical diagnosis and treatment ability.Methods Combined with the medical history,clinical symptoms,signs and auxiliary examination in the case report,the eye movement characteristics and related nerve pathways of the sixteen-and-a-half syndromes were comprehensively analyzed to locate the pons lesions.Results In this patient,the Ⅷ cranial nerve(vestibulo-cochlear)simply involved the left vestibule,and there were clinical evidences of spontaneous nystagmus with left torsional upbeat and reduced function of the left saccule pathway.The lesions at the pontine showed vertical gaze-evoked nystagmus.Conclusions In the sixteen-and-a-half syndrome,the vestibular cochlear nerve is involved and may involve only the vestibular part without hearing impairment.The lesion of pons may result in sixteen and a half syndromes,and may also result in vertical gaze-evoked nystagmus.
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