首页|新型抗癫痫发作药物对认知功能的影响的研究进展

新型抗癫痫发作药物对认知功能的影响的研究进展

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癫痫是一种由于大脑神经元高度同步化异常放电引起的以发作性、短暂性、重复性、刻板性为特点的大脑功能障碍综合征,常常合并认知功能障碍.目前抗癫痫发作药物治疗为临床治疗的最主要方法,传统抗癫痫发作药物大多可致认知功能障碍,新型抗癫痫发作药物对认知功能的影响尚不完全明确.本文结合国内外相关文献,就新型抗癫痫发作药物对认知功能的影响及其可能的相关作用机制做一综述,以期临床医师在癫痫的诊治过程中重视认知功能,帮助临床医师认识到抗癫痫发作药物对认知功能的影响,从而合理地为患者选择抗癫痫发作药物.
Research progress on the effect of new anti-seizure medications on cognitive function
Epilepsy is a kind of brain dysfunction syndrome characterized by paroxysmal,transient,repetitive and rigid characteristics caused by abnormal discharge of highly synchronized neurons in the brain.Epilepsy is often accompanied by cognitive dysfunction.At present,anti-seizure medications are the most important methods of clinical treatment.Most of the traditional anti-seizure medications can cause cognitive dysfunction,and the influence of new anti-seizure medications on cognitive function is not completely clear.This paper reviews the influence of new anti-seizure medications on cognitive function and the possible related mechanisms of action based on relevant literature at home and abroad.It is expected that clinicians should pay attention to cognitive function in the process of diagnosis and treatment of epilepsy,and help clinicians realize the influence of anti-seizure medications on cognitive function,and rationally choose anti-seizure medications for patients.

epilepsycognitive dysfunctionnew anti-seizure medications

黄格格、杨建仲、牛永利

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030012 太原,山西医科大学第五临床医学院

山西省人民医院神经内科

癫痫 认知功能障碍 新型抗癫痫发作药物

2024

临床神经病学杂志
南京医科大学附属脑科医院

临床神经病学杂志

CSTPCD
影响因子:1.778
ISSN:1004-1648
年,卷(期):2024.37(2)
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