Study on the correlation between scattered infarction in the radial coronary infarcts of the lenticulostriate artery and early neurological deterioration
Objective To investigate the correlation between scattered infarction in the radial coronary area of the lenticulostriate artery(LSA)and early neurological deterioration(END).Methods A total of 164 patients diagnosed with LSA infarction who were hospitalized in the Stroke Center of Zhengzhou People's Hospital from January 2018 to September 2023 were retrospectively included.According to the location of infarct lesions,the cases were divided into single lesions at the origin of the LSA(n=103)and multiple scattered lesions originating from the LSA(n=61).The clinical features,risk factors and prognosis analysis of the two groups were observed and compared.Results Among 164 patients,END occurred in 49 cases,and 115 cases did not have END.Univariate analysis results showed that compared to a single lesion,the incidence of END was significantly higher in cases where the infarction originated from the LSA and presented as multiple scattered lesions[27(55.1％)vs.22(44.9％),P＜0.05].Compared to anterior infarctions,the incidence of END was significantly higher in patients with posterior infarctions[39(79.6％)vs.10(20.4％),P＜0.05].Multivariate Logistic regression analysis,adjusted for confounding factors,indicated that infarctions originating from the LSA with multiple scattered lesions(OR=3.669,95％CI:1.696-7.939,P=0.001)and posterior infarctions(OR=2.303,95％CI:1.005-5.279,P=0.049)were independently associated with the occurrence of END.After 3 months of follow-up,compared with the single lesion,the proportion of patients with infarction originating from LSA and dispersed in multiple places had a significantly reduced prognosis(45.9％vs.91.3％),and the clinical outcomes were poor.Conclusions Scattered infarcts in the radiate crown area of the LSA and posterior infarctions are independent risk factors for the occurrence of END in LSA infarctions.Patients with scattered infarcts in the radiate crown area are more likely to develop END,leading to poor prognosis.
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