Glioblastoma(GBM)is one of the most common primary intracranial malignant tumors with high recurrence rate and high mortality.The current standard treatment option is surgery,concurrent chemoradiotherapy,and adjuvant temozolomide chemotherapy.Tumor treating fields(TTFields)is an emerging tumor treatment,and when combined with standard treatment,the progression-free survival and overall survival of GBM patients can be significantly improved.Based on the results of multiple clinical researches,TTFields has been approved for marketing in China and abroad,and has been recommended by guidelines and consensus.This article will focus on the development of TTFields and summarise the landscape of TTFields clinical trials in GBM.
tumor treating fieldsmechanism of actionglioblastomaclinical research
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