Objective To explore the influence of laboratory frailty index(FI-Lab)scores on postoperative complications in unruptured aneurysm patients.Methods The clinical data of 125 patients with unruptured aneurysm in the First Affiliated Hospital of Soochow University from January 2019 to January 2022 were analyzed retrospectively.The FI-Lab scores was employed to separate patients into two groups,the frail group(n=29)and the non frail group(n=96),and the postoperative complications of the two were then compared.Subsequently,patients were divided into two groups;the complication group(n=28),and the non-complication group(n=97).Statistical analysis was conducted to examine the sex,age,frailty,aneurysm location,diabetes,hypertension,operation duration,intraoperative bleeding volume,postoperative drainage volume of the patients,in order to investigate the risk factors of postoperative complications.Results A total of 28 out of the 125 people with unruptured aneurysms experienced postoperative complications.Results of univariate analysis showed that age(P=0.029),frailty(P=0.001),diabetes(P=0.046),hypertension(P=0.044),and operation duration(P=0.040)had a significant influence on the occurrence of postoperative complications.There was no statistically significant association between postoperative complications and gender,aneurysm site,intraoperative bleeding volume,or postoperative drainage volume(P>0.05).The logistic regression analysis indicated that frailty(FI-Lab ≥0.3)was a significant independent risk factor for postoperative complications in unruptured aneurysm surgery patients(P=0.021,OR=3.881).Conclusions FI-Lab score ≥ 0.3 has been suggested to be a potential indicator of postoperative complications in unruptured aneurysm surgery patients.Additionally,FI-Lab scores may be a useful tool in forecasting the prognosis of those who have undergone unruptured aneurysm surgery.