Objective To investigate the clinical manifestations,diagnosis and treatment for recurrent primary intracranial melanoma.Methods A case of recurrent primary intracranial melanoma which confirmed by pathological examination admitted to Nantong University Affiliated Hospital in April 2022 was analyzed retrospectively,and the clinical manifestations,imaging features,pathological diagnosis and treatment methods of intracranial melanoma were summarized in combination with relevant literature.Results Total resection was performed in the first operation,and the pathological report was malignant melanoma.No radiotherapy and chemotherapy were performed after the operation.The follow-up period was more than 7 years,and there was no recurrence for 5 months after the second operation.Conclusions Long-term survival of primary intracranial melanoma is rare,and its imaging manifestations are variable,and easy to misdiagnose before surgery.Total surgical resection is the key,and aggressively repeated surgical resection remains beneficial for recurrent cases.The effect of radiotherapy and chemotherapy are uncertain.Indeed,surgery combined with stereotactic radiosurgery(SRS),targeted therapy,immunotherapy seem to be the best solution for primary intracranial melanoma.
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