Objective To explore the relationship between computer tomography(CT)score and serum lactic acid(LA),neuron specific enolase(NSE),C-reactive protein(CRP)in patients with acute craniocerebral injury(ACI)and their predictive value for prognosis.Methods A total of 50 patients with ACI admitted to Dongtai People's Hospital were collected as disease group between January 2020 and January 2022.According to scores of Glasgow outcome scale(GOS)after treatment,they were divided into good prognosis group(32 cases)and poor prognosis group(18 cases).A total of 50 healthy controls during the same period were enrolled as health group.The evaluation value of serum LA,NSE,CRP levels and CT score for prognosis of ACI patients was assessed by receiver operating characteristic curve(ROC).Results The levels of serum LA,NSE and CRP in disease group were higher than those in healthy group(P＜0.05),and which were higher in poor prognosis group than good prognosis group.Spearman correlation analysis showed that levels serum LA,NSE and CRP were positively correlated with CT score(r=0.431,0.345,0.226,P＜0.05).ROC analysis showed that area under curve(AUC)of LA combined with NSE,CRP and CT score for predicting prognosis of acute intracranial infection was greater than that of single index(P＜0.05).Conclusions CT score is positively correlated with levels of serum LA,NSE and CRP in ACI patients at admission.The combined detection of the four indexes has certain evaluation value for prognosis.
acute craniocerebral injuryCT scorelactic acidneuron specific enolaseC-reactive proteinprognosis
维普
万方数据
