Objective To investigate the effect of middle meningeal artery(MMA)dilation on the pathogenesis and prognosis of chronic subdural hematoma(CSDH),and to provide a theoretical basis for MMA embolization in the treatment of CSDH.Methods The clinical data of 48 patients with unilateral CSDH who underwent burr hole and drainage surgery in Affiliated Jiangyin Clinical College of Xuzhou Medical University from January 2018 to June 2022 were analyzed retrospectively,including magnetic resonance angiography of MMA,hematoma absorption at 1 week and 1 month after surgery.The diameter of MMA on the affected side was significantly expanded and the postoperative hematoma absorption of different patients was compared and analyzed.Results The mean diameter of MMA in 48 CSDH patients was significantly larger than that in healthy side[(1.738±0.224)mm vs(1.361±0.184)mm,t=9.021,P<0.001)],there was no significant difference in hematoma absorption between the MMA dilatation group and the MMA non-dilatation group at 1 week after operation(Z=-0.69,P=0.945),and there was significant difference in hematoma absorption between the MMA dilatation group and the MMA non-dilatation group at 1 month after operation(Z=-2.283,P=0.022).The rate of hematoma resorption was lower in the MMA dilated group than in the MMA non-dilated group.Conclusions MMA is the main blood supply artery of CSDH advection neovascularization.MMA dilatation plays a key role in the occurrence and progression of CSDH hematoma,which is not conducive to the prognosis of CSDH patients.