Objective To observe the effect of radiofrequency ablation in patients with heart failure complicated by persistent atrial fibrillation(PAF).Methods A total of 127 patients with heart failure complicated by PAF were randomly divided into observation(n=63)and control(n=64)group,controls received amiodarone medication,and observation group did radiofrequency ablation on the basis of controls.Both groups were treated for continuous 3 months and followed up for 6 months after operation.After treatment,clinical efficacy and re-admission for heart failure were compared between two groups,before and after treatment such indexes were compared between two groups as cardiac function indicators(Left Atrium Diameter[LAD],Left Ventricular End-Diastolic Diameter[LVDD],and Left Ventricular Ejection Fraction[LVEF]),qualities of life(score on the Minnesota Living with Heart Failure Questionnaire[MLHFQ]),and serological indicators(Tissue Inhibitor of Metal Protease-1[TIMP-1]and Matrix Metalloprotein-9[MMP-9])levels.Results After treatment,the clinical total effective rate was higher in observation than control group(P＜0.05).After treatment LAD and Radiofrequency ablation can effectively improve the cardiac functions of patients with heart failure complicated by PAF and deserves clinical promotion.
关键词
射频消融术/心力衰竭/持续性心房颤动/左心功能/生活质量/血清学指标
Key words
radiofrequency ablation/heart failure/persistent atrial fibrillation/left ventricular function/quality of life/serological indicator
维普
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