Clinical effectiveness of electrical stimulation therapy for patients with vestibular migraine
Objective To explore the clinical effectiveness of electrical stimulation therapy(EST)for patients with vestibular migraine(VM).Methods A total of 116 VM patients were divided into research and control group according to random number table,with 58 ones in each.Controls were treated with flunarizine capsules and research group was plus the EST on the basis of controls.Before and after treatment,such indexes were compared between two groups as sleep qualities(Pittsburgh Sleep Quality Index[PSQI]scores),degrees of headache(Numeric Rating Scale[NRS]scores),vertigo symptoms(Dizziness Handicap Inventory[DHI]scores),anxious-depressive emotions(Self-Rating Anxiety Scale[SAS]and Self-Rating Depression Scale[SDS]scores),and serum neurotransmitters(Nitric Oxide[NO],Calcitonin Gene-Related Peptide[CGRP],Endothelin-1[ET-1],Substance P[SP],and 5-Hydroxytryptamine[5-HT])levels,and clinical effectiveness and the occurrence of adverse reactions of two groups recorded and compared.Results After treatment,scores on the PSQI,NRS,DHI,SAS,and SDS in both groups were lower compared with pre-treatment and so were those in research than control group(P＜0.01).After treatment,serum NO,ET-1 and SP levels in both groups were lower,CGRP)and 5-HT higher compared with pre-treatment,and research group was better than controls(P＜0.01).The total effective rate was higher and the incidence of adverse reactions lower in research than control group(P＜0.05 or 0.01).Conclusion Electrical stimulation therapy has a definite effect and high safety in the treatment of VM patients,can improve clinical symptoms and quality of life,and which deserves clinical promotion.
万方数据
维普
