摘要
全血是有史以来最早使用的血液制品,但在20世纪70年代,随着成分输血治疗的出现,全血几乎从血库清单中消失了.近年来,在成功军事经验的基础上,全血用于出血性创伤患者复苏又重新引起了输血界的关注,并逐渐将其由军事领域引入到民用救治环境中.本文基于国内外全血输注指南以及发表的相关研究,就全血的分类、全血使用历史、全血储存及血小板保护、全血白细胞去除、全血病原灭活及科学精准输注全血亟待解决的问题等进行综述,展望其未来发展方向,为更广泛地重新认识引入全血,推动输血医学治疗的发展提供参考.
Abstract
Whole blood was the earliest blood product ever used,however,with the advent of component transfusion treatments,whole blood all but disappeared from blood bank lists in the 1970 s.In recent years,based upon the successful military experience,the use of whole blood to resuscitate patients with hemorrhagic trauma has again attracted the attention of the blood transfusion circle,and it has gradually been introduced from the military field to the civilian treatment settings.Based on the guidelines for whole blood transfusion at home and abroad and related published studies,this paper reviews the classification of whole blood,history of whole blood use,whole blood storage and platelet protection,removal of whole blood white blood cells,inactivation of whole blood pathogens,and urgent problems to be solved in scientific and accurate transfusion of whole blood,and looks forward to its future development direction,providing reference for the introduction of whole blood more widely,and the development of blood transfusion medicine.
维普
万方数据