Objective The research status and trends of human bone marrow mesenchymal stem cells(hBMMSC)in the past 30 years were quantitatively analyzed by CiteSpace in WOS core database.Methods WOS core database was used to search hBMMSC related articles published worldwide from 1995 to 2023,and CiteSpace software was used to conduct bibliometric analysis on the number of publications,countries,institutions,disciplines,authors,keywords and other data.Results A total of 4 280 articles were included in this study,of which 1 194 were published in the United States,95 were published by Harvard University,25 were published by Chen Guoping and Tuan Rocky S respectively,and 1 024 were published by cell biology.The most high-frequency keywords are tissue engineering after clustering.Conclusion In the past nearly 30 years,hBMMSC related research has continued to increase,and the research focus has been transformed from early basic research including molecular mechanism,pathogenic characteristics,and developmental biology to clinical application research,focusing on tissue engineering research and development,hBMMSC microvesicle research,and the relationship between hBMMSC and cancer,etc.This study can provide guidance for in-depth research on hBMMSC.