临床误诊误治2023,Vol.36Issue(10) :14-17.DOI:10.3969/j.issn.1002-3429.2023.10.004

以肾外多系统表现首诊的慢性肾衰竭临床误诊分析

Clinical Misdiagnosis of Chronic Renal Failure with Extrarenal Multi-system Manifestations at Initial Diagnosis

赵灿 李关静 邢立朝 冯翠娟 侯君贤
临床误诊误治2023,Vol.36Issue(10) :14-17.DOI:10.3969/j.issn.1002-3429.2023.10.004

以肾外多系统表现首诊的慢性肾衰竭临床误诊分析

Clinical Misdiagnosis of Chronic Renal Failure with Extrarenal Multi-system Manifestations at Initial Diagnosis

赵灿 1李关静 2邢立朝 3冯翠娟 3侯君贤4
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作者信息

  • 1. 071000 河北保定,中国中医科学院广安门医院保定医院肾病风湿科
  • 2. 071000 河北保定,保定市第二医院肾内科
  • 3. 071000 河北保定,中国中医科学院广安门医院保定医院透析室
  • 4. 071000 河北保定,清苑区人民医院肾内科
  • 折叠

摘要

目的 分析慢性肾衰竭(CRF)的肾外多系统表现及早期误诊原因.方法 回顾性分析2021 年7 月—2023 年2 月收治的曾误诊的CRF 14 例的临床资料.结果 4 例主要症状为皮肤干燥无光泽、皮肤瘙痒、毛发枯萎,误诊为皮肤瘙痒症;3 例因疲乏无力、头晕、心悸及面色苍白,查血红蛋白降低,误诊为贫血;3 例因不同程度头痛、头晕、视物模糊、血压升高,误诊为原发性高血压病;4 例因不同程度食欲不振、恶心呕吐、腹部不适,结合纤维胃镜检查结果,误诊为慢性胃炎.14 例予针对性治疗后病情改善不明显,会诊后行尿常规、肾功能及肾脏B超检查,综合分析病情后明确诊断CRF.误诊时间1~3 个月.14 例确诊后予原发病、诱因治疗和饮食疗法及透析治疗后血肌酐、尿素下降,代谢性酸中毒、电解质紊乱、贫血得到纠正,随访1 年,病情稳定.结论 CRF早期症状常不典型,极易误诊,临床对以肾外系统表现首诊的患者,应全面分析病情,及时行尿常规、肾功能及肾脏影像学检查,可有效避免本病误诊.

Abstract

Objective To analyze the extrarenal multi-system manifestations and early causes of misdiagnosis of chro-nic renal failure(CRF).Methods The clinical data of 14 patients with misdiagnosed CRF admitted from July 2021 to Feb-ruary 2023 were retrospectively analyzed.Results Four cases were misdiagnosed as pruritus due to main symptoms,inclu-ding dry,dull skin,pruritus and withered hair.Three cases were misdiagnosed as anemia due to fatigue,dizziness,palpita-tion and pale complexion as well as a decrease in hemoglobin.Three cases were misdiagnosed as primary hypertension due to varying degrees of headache,dizziness,blurred vision and elevated blood pressure,and 4 cases were misdiagnosed as chronic gastritis due to different degrees of loss of appetite,nausea and vomiting,and abdominal discomfort,combined with the results of fiberscope.The condition of 14 cases did not improve significantly after targeted treatment.After consultation,urine rou-tine,kidney function and kidney B-ultrasound were performed,and CRF was confirmed after comprehensive analysis of the condition.The duration of misdiagnosis was 1-3 months.After diagnosis,blood creatinine and urea levels were decreased in 14 cases after treatment for primary disease,inducement treatment,and diet therapy,and metabolic acidosis,electrolyte dis-turbance and anemia were corrected.The condition was stable at 1-year follow-up.Conclusion The early symptoms of CRF are often atypical,which can easily lead to misdiagnosis.In clinical practice,patients with extrarenal system symptoms at ini-tial visit should be comprehensively analyzed,and timely urine routine,renal function and renal imaging examinations can ef-fectively avoid misdiagnosis of this disease.

关键词

肾功能衰竭,慢性/误诊/皮肤瘙痒症/贫血/原发性高血压病/慢性胃炎/尿常规/超声检查

Key words

Renal failure,chronic/Misdiagnose/Skin pruritus/Anemia/Primary hypertension/Chronic gastritis/Urine routine/Ultrasonography

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基金项目

保定市科技计划项目(2141ZF107)

出版年

2023
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
被引量1
参考文献量13
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