临床误诊误治2023,Vol.36Issue(10) :54-58.DOI:10.3969/j.issn.1002-3429.2023.10.013

PI-RADS v2评分联合表观扩散系数在前列腺癌中的诊断价值分析

Analysis of the Diagnostic Value of PI-RADS v2 Combined Apparent Diffu-sion Coefficient in Prostate Cancer

刘婷婷 潘锋 李昊 王晓辉 王洪兴 高成林
临床误诊误治2023,Vol.36Issue(10) :54-58.DOI:10.3969/j.issn.1002-3429.2023.10.013

PI-RADS v2评分联合表观扩散系数在前列腺癌中的诊断价值分析

Analysis of the Diagnostic Value of PI-RADS v2 Combined Apparent Diffu-sion Coefficient in Prostate Cancer

刘婷婷 1潘锋 1李昊 1王晓辉 1王洪兴 1高成林2
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作者信息

  • 1. 100076 北京,北京航天总医院影像中心
  • 2. 233000 安徽 蚌埠,蚌埠市第一人民医院泌尿外科
  • 折叠

摘要

目的 探究前列腺影像报告和数据系统第二版(PI-RADS v2)评分联合表观扩散系数(ADC)对前列腺癌的诊断价值.方法 选取2017 年7 月—2021 年7 月治疗的80 例前列腺疾病患者为研究对象,根据前列腺穿刺活检结果分为前列腺癌组51 例和非前列腺癌组29 例.所有患者在病情稳定状况下进行MRI平扫,测量ADC值,进行PI-RADS v2 评分.比较2 组PI-RADS v2 评分及ADC值,采用受试者工作特征曲线评估PI-RADS v2 评分联合ADC值对前列腺癌的诊断效能.结果 前列腺癌组PI-RADS v2 评分明显高于非前列腺癌组,ADC值明显低于非前列腺癌组(P<0.01).PI-RADS v2 评分(阈值为 4 分)诊断前列腺癌的敏感度为 82.35%,特异度为 75.86%,准确度为80.00%,曲线下面积(AUC)为0.829;ADC值(阈值为 850×10-6 mm2/s)诊断前列腺癌的敏感度为 78.43%,特异度为79.31%,准确度为78.75%,AUC为0.816;二者联合诊断前列腺癌的敏感度为92.16%,特异度为89.66%,准确度为91.23%,AUC为0.868.二者联合诊断前列腺癌的 AUC 明显大于 PI-RADS v2 评分和 ADC 值单独诊断(P<0.05).结论 PI-RADS v2 评分联合ADC值对前列腺癌有较好的诊断价值,且较单一检测的准确度更高.

Abstract

Objective To explore the diagnostic value of prostate imaging reporting and data systemversion 2(PI-RADS v2)combined with apparent diffusion coefficient(ADC)in prostate cancer.Methods A total of 80 patients with prostate disease who were treated in our hospital from July 2017 to July 2021 were included in this study.According to the re-sults of prostate biopsy,all patients were divided into prostate cancer group(n =51)and non-prostate cancer group(n =29).All patients underwent plain MRI in stable condition,for measurement of ADC values,and scoring of PI-RADS v2.PI-RADS v2 scores and ADC of the two groups were compared,and receiver operating characteristic(ROC)curve was used to evaluate the diagnostic efficacy of PI-RADS v2 scores combined with ADC values for prostate cancer.Results PI-RADS v2 scores were higher in prostate cancer group than in non-prostate cancer group,while ADC value was significantly lower than that in non-prostate cancer group(P<0.01).The sensitivity of PI-RADS v2 scores(with the threshold of 4 points)in the diagnosis of prostate cancer was 82.35%,the specificity was 75.86%,the accuracy was 80.00%,and the area under the ROC curve(AUC)was 0.829.The sensitivity of ADC value(with the threshold of 850×10-6 mm2/s)in the diagnosis of prostate canc-er was78.43%,the specificity was79.31%,the accuracy was 78.75%,and the AUC was 0.816;the sensitivity of com-bined detection in the diagnosis of prostate cancer was 92.16%,the specificity was 89.66%,the accuracy was 91.23%,and the AUC was 0.868.The AUC of combined diagnosis was significantly larger than that of PI-RADS v2 scores and ADC alone.Conclusion The PI-RADS v2 scores combined with ADC values has good diagnostic value for prostate cancer and is more ac-curate than a single detection.

关键词

前列腺肿瘤/PI-RADS/v2/表观扩散系数/磁共振成像/特异度/敏感度/诊断/受试者工作特征

Key words

Prostatic neoplasms/PI-RADS v2/Apparent diffusion coefficient/Magnetic resonance imaging/Speci-ficity/Sensitivity/Diagnosis/Receiver operating characteristic

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基金项目

安徽省重点研究与开发计划项目(1704f0804038)

出版年

2023
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
参考文献量28
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