Effect of Ultrasound-guided Transversus Abdominis Plane Block on Stress Response and Analgesic Effect in Patients Undergoing Laparoscopic Chole-cystectomy under General Anesthesia
Effect of Ultrasound-guided Transversus Abdominis Plane Block on Stress Response and Analgesic Effect in Patients Undergoing Laparoscopic Chole-cystectomy under General Anesthesia
Objective To investigate the effects of ultrasound-guided transversus abdominis plane block(TAPB)on stress response and analgesia in patients undergoing laparoscopic cholecystectomy under general anesthesia.Methods Sixty patients undergoing laparoscopic cholecystectomy admitted to our hospital from May 2022 to October 2022 were selected.Ac-cording to different anesthesia methods,they were divided into observation group and control group,with 30 cases in each group.The observation group was given ultrasound-guided TAPB on the basis of general anesthesia,and the control group was given general anesthesia.Adrenocorticotropin(ACTH)and cortisol(Cor)before anesthesia and at 6,12,and 24 h after an-esthesia,visual analogue scale(VAS)scores at 6,12,24 and 48 h after anesthesia,spontaneous respiratory recovery time,recovery time,extubation time,intraoperative sufentanil dosage,and the occurrence of adverse reactions at 48 h after opera-tion were compared between the two groups.Results At 6,12 and 24 h after operation,ATCH and Cor in the two groups were higher than those before anesthesia,but ATCH and Cor in observation group were lower than those in control group(P＜0.05).The VAS scores of the observation group were lower than those of the control group at 6,12 and 24 h after operation(P＜0.05).After operation,the recovery time of spontaneous respiration,recovery time,extubation time and intraoperative sufentanil dosage in the observation group were shorter or less than those in the control group(P＜0.01).At 48 h after opera-tion,the incidence of adverse reactions in the observation group(3/30,10.00%)was lower than that in the control group(10/30,33.00%)(P＜0.05).Conclusion TAPB has obvious analgesic effect in patients undergoing laparoscopic chole-cystectomy under general anesthesia,which can reduce stress response,improve postoperative recovery-related indexes,and have fewer adverse reactions.
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