临床误诊误治2023,Vol.36Issue(10) :149-152.DOI:10.3969/j.issn.1002-3429.2023.10.031

乙酰谷酰胺治疗神经损伤的研究进展

Research Progress in the Treatment of Nerve Injury with Aceglutamide

赵彩霞 王昌玮 庞鑫鑫 齐洪武
临床误诊误治2023,Vol.36Issue(10) :149-152.DOI:10.3969/j.issn.1002-3429.2023.10.031

乙酰谷酰胺治疗神经损伤的研究进展

Research Progress in the Treatment of Nerve Injury with Aceglutamide

赵彩霞 1王昌玮 2庞鑫鑫 1齐洪武3
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作者信息

  • 1. 050082 石家庄,联勤保障部队第九八〇医院药剂科
  • 2. 050082 石家庄,联勤保障部队第九八〇医院病理科
  • 3. 050082 石家庄,联勤保障部队第九八〇医院神经外科
  • 折叠

摘要

神经损伤在世界范围内仍是导致机体残疾和死亡的主要原因,神经损伤主要包括创伤性脑损伤和缺血性脑卒中等.乙酰谷酰胺是临床治疗神经损伤的常用药物,可透过血脑屏障作用于脑组织及神经系统.现已被证明,乙酰谷酰胺可提高神经系统可塑性,促进神经细胞代谢,对创伤性脑损伤、缺血性脑卒中等各种原因所致的神经损伤具有确切疗效.本研究就乙酰谷酰胺治疗神经损伤的研究进展做一综述.

Abstract

Objective Nerve injury is still a major cause of disability and death worldwide,including traumatic brain injury and ischemic stroke.Aceglutamide is a commonly used drug in clinical treatment of nerve injury,which can act on brain tissue and nervous system through the blood-brain barrier.It has been proved that Aceglutamide can improve the plastici-ty of the nervous system,promote the metabolism of nerve cells,and have a definite effect on nerve injury caused by various reasons such as traumatic brain injury and ischemic stroke.In this study,the research progress of Aceglutamide in the treat-ment of nerve injury is reviewed.

关键词

乙酰谷酰胺/神经损伤/药理作用/抗氧化/抑制炎症反应/抗缺血/再灌注损伤/抑制神经细胞凋亡/综述

Key words

Acetylglutamide/Nerve injury/Pharmacological effect/Anti-oxidation/Inhibition of inflammatory re-sponse/Anti-ischemia/reperfusion injury/Inhibition of nerve cell apoptosis/Review

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基金项目

石家庄市科学技术研究与发展计划项目(201201043)

出版年

2023
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
被引量1
参考文献量27
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