临床误诊误治2023,Vol.36Issue(12) :6-9,18.DOI:10.3969/j.issn.1002-3429.2023.12.002

肿瘤标志物升高的肺隔离症误诊分析

Analysis of Misdiagnosis of Pulmonary Sequestration with Elevated Tumor Markers

陈玉 赵松林 魏兵 聂秀红
临床误诊误治2023,Vol.36Issue(12) :6-9,18.DOI:10.3969/j.issn.1002-3429.2023.12.002

肿瘤标志物升高的肺隔离症误诊分析

Analysis of Misdiagnosis of Pulmonary Sequestration with Elevated Tumor Markers

陈玉 1赵松林 1魏兵 1聂秀红1
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作者信息

  • 1. 100053 北京,首都医科大学宣武医院呼吸与危重症医学科
  • 折叠

摘要

目的 探讨肿瘤标志物升高的肺隔离症(PS)临床特点及误诊原因、防范措施.方法 回顾性分析2019 年6 月—2022 年6 月收治的曾误诊为肺癌的伴肿瘤标志物升高的PS3 例的临床资料,并复习相关文献.结果 3 例分别因咳嗽、咳痰2 周,咳嗽伴发热2 周,发现左下肺占位2 个月入院.3 例均无反复肺部感染病史,胸部CT检查均显示为实性团块影(左下肺2 例、右下肺1 例),且至少1 项肿瘤标志物升高.仅1 例术前行强化CT检查.术前皆误诊为肺癌,皆行手术切除,术后病理检查明确诊断为PS.术后 3 个月复查,3 例肿瘤标志物均恢复正常.结论 PS可导致肿瘤标志物升高,易误诊为恶性肿瘤,临床应仔细甄别,避免误诊.

Abstract

Objective To investigate the clinical characteristics,causes of misdiagnosis and preventive measures of pulmonary sequestration(PS)with elevated tumor markers.Methods The clinical data of PS 3 patients with elevated tumor markers who had been misdiagnosed as lung cancer were retrospectively analyzed from June 2019 to June 2022,and the rele-vant literature was reviewed.Results Three patients were admitted due to cough and phlegm for 2 weeks,cough with fever for 2 weeks,and a space occupying lesion in the left lower lung for 2 months,respectively.There was no history of recurrent pulmonary infection in the 3 patients.CT examination of chest showed solid mass shadow(in the lower left lung in two patients and in the lower right lung in one patient)and at least one tumor marker was elevated.Only 1 patient underwent enhanced CT examination before operation.All patients were misdiagnosed as lung cancer before operation and underwent surgical resection.The diagnosis was confirmed as PS by pathological examination after operation.At 3 months after the operation,the tumor markers of 3 patients returned to normal.Conclusion PS can lead to the increase of tumor markers,which is more likely to be misdiagnosed as malignant tumor,and should be carefully screened in clinical setting to avoid misdiagnosis.

关键词

肺隔离症/误诊/肺肿瘤/癌胚抗原/癌抗原19-9/癌抗原125/体层摄影术,螺旋计算机/病理检查

Key words

Pulmonary sequestration/Misdiagnosis/Lung neoplasms/Carcinoembryonic antigen/Carcinoma antigen 19-9/Carcinoma antigen 125/Tomography,spiral computed/Pathological examination

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基金项目

2022年度北京市重大疫情防治重点专科建设项目(2-1-2-0085-02)

出版年

2023
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
参考文献量6
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