临床误诊误治2023,Vol.36Issue(12) :27-31.DOI:10.3969/j.issn.1002-3429.2023.12.007

甲状腺癌CT误诊为结节性甲状腺肿、甲状腺腺瘤的临床分析

Clinical Analysis of Thyroid Carcinoma Misdiagnosed by CT as Nodular Goiter and Thyroid Adenoma

张亚杰 于泽洋 项昆 王卓
临床误诊误治2023,Vol.36Issue(12) :27-31.DOI:10.3969/j.issn.1002-3429.2023.12.007

甲状腺癌CT误诊为结节性甲状腺肿、甲状腺腺瘤的临床分析

Clinical Analysis of Thyroid Carcinoma Misdiagnosed by CT as Nodular Goiter and Thyroid Adenoma

张亚杰 1于泽洋 2项昆 3王卓1
扫码查看

作者信息

  • 1. 063000 河北 唐山,开滦总医院影像科
  • 2. 063015 河北 唐山,唐山市第二医院医学影像科
  • 3. 063006 河北 唐山,唐山市协和医院医学影像科
  • 折叠

摘要

目的 分析甲状腺癌CT误诊为结节性甲状腺肿、甲状腺腺瘤的原因及防范措施.方法 回顾性分析2020 年2 月—2022 年3 月收治的甲状腺癌误诊病例12 例的临床资料.结果 12 例均以颈前无痛性单发肿物(右侧5 例、左侧7 例)就诊,甲状腺均增大,5 例可触及多个颈部增大淋巴结;出现声嘶、呼吸困难等压迫症状 5 例;肿物质硬,吞咽时活动性差5 例.12 例中形状不规则7 例,边界清楚4 例;3 例肿物邻近气管、肌肉或血管浸润包埋,4 例包膜欠完整,5 例颈部淋巴结增大.12 例增强扫描均表现为不均匀强化.误诊为甲状腺腺瘤7 例、结节性甲状腺肿 5 例,均拟行手术治疗,经术中冰冻切片及术后病理检查证实为甲状腺癌,病理类型为乳头状腺癌.误诊时间 2~3d.12例中行患侧腺叶切除术8 例,患侧腺叶+峡部切除术4 例,同时行患侧增大颈部淋巴结清除术 5 例,术后予以放疗 6例.12 例术后均口服甲状腺素片防止复发.术后随访1 年,均存活且未复发.结论 甲状腺癌患者早期常无明显症状,多以无痛性颈部肿物就诊,若CT影像不典型,未及早行针刺细胞学病理检查,易导致术前误诊.提高对本病的警惕性,认真询问病史,仔细查体,熟知CT影像学征象,及早行针刺细胞学病理检查,可有效避免术前误诊.

Abstract

Objective To analyze the causes and preventive measures of thyroid cancer misdiagnosed by CT as nodu-lar goiter and thyroid adenoma.Methods The clinical data of 12 patients with thyroid cancer misdiagnosed in our hospital from February 2020 to March 2022 were retrospectively analyzed.Results All 12 patients were treated with single,painless mass in the anterior neck(5 cases on the right side and 7 cases on the left side),and all of them had enlarged thyroid gland.Multiple enlarged cervical lymph nodes were palpated in 5 patients,and pressure symptoms such as hoarseness and dyspnea were found in 5 patients.The swelling material was hard and the activity of swallowing was poor in 5 patients.Of the 12 ca-ses,7 had irregular shape and 4 had clear boundary.In 3 cases,the tumor was infiltrated near the trachea,muscle or blood vessel,the capsule was incomplete in 4 cases,and the cervical lymph nodes were enlarged in 5 cases.All the 12 cases showed uneven enhancement by enhanced scan.The patients were misdiagnosed as thyroid adenoma in 7 cases and nodular goiter in 5 cases,all of which were to be treated by operation.They were confirmed as thyroid cancer by intraoperative frozen section and postoperative pathological examination.The pathological type was papillary adenocarcinoma.The duration of mis-diagnosis was 2-3 days.Among the 12 cases,8 cases underwent adenolobectomy,4 cases underwent adenolobectomy + isth-musectomy,5 cases underwent removal of enlarged neck lymph node on the affected side,and postoperative radiotherapy was given to 6 cases.Oral thyroxine tablets were given to 12 cases to prevent recurrence.At 1-year follow-up,all patients survived without recurrence.Conclusion Patients with thyroid cancer often have no obvious symptoms in the early stage and mostly presented with painless neck masses.If the CT images are not typical and the cytological examination of acupuncture is not performed early,preoperative misdiagnosis is more likely to occur.It is necessary to improve the vigilance of the disease,carefully inquire about the history,carefully perform physical examination,be familiar with CT imaging signs,conduct early needle aspiration cytology and pathological examination,to effectively avoid preoperative misdiagnosis.

关键词

甲状腺癌/误诊/甲状腺腺瘤/结节性甲状腺肿/良恶性/体层摄影术,螺旋计算机/活组织检查,针吸/鉴别诊断

Key words

Thyroid cancer/Misdiagnosis/Thyroid adenoma/Nodular goiter/Benign and malignant/Tomography,spiral computed/Biopsy,needle/Differential diagnosis

引用本文复制引用

基金项目

河北省卫健委重点课题计划(20201546)

出版年

2023
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
参考文献量21
段落导航相关论文