临床误诊误治2023,Vol.36Issue(12) :86-90.DOI:10.3969/j.issn.1002-3429.2023.12.018

基于Nomogram模型预测颅脑损伤术后院内感染风险及防控措施探讨

Prediction of Nosocomial Infection Risk and Prevention and Control Meas-ures after Craniocerebral Injury Based on Nomogram Model

张倩 李正
临床误诊误治2023,Vol.36Issue(12) :86-90.DOI:10.3969/j.issn.1002-3429.2023.12.018

基于Nomogram模型预测颅脑损伤术后院内感染风险及防控措施探讨

Prediction of Nosocomial Infection Risk and Prevention and Control Meas-ures after Craniocerebral Injury Based on Nomogram Model

张倩 1李正2
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作者信息

  • 1. 071000 河北 保定,保定市第一中心医院感控处
  • 2. 071000 河北 保定,保定市第一医院骨科
  • 折叠

摘要

目的 观察Nomogram模型在颅脑损伤术后院内感染风险预测中的价值.方法 回顾分析 2021 年 1月—2022 年12 月收治的颅脑损伤 240 例的临床资料,统计术后院内感染情况,筛选颅脑损伤术后院内感染影响因素,并采用R软件构建预测院内感染的Nomogram模型,采用受试者工作特征曲线进行效能评估.结果 240 例颅脑损伤患者中,院内感染发生率为15.83%,其中呼吸系统感染位居第一;共检出82 株病原菌,以革兰阳性菌为主;年龄≥60 岁、合并糖尿病、开放性损伤、入院格拉斯哥昏迷评分法评分<8 分、低蛋白血症、气管切开、手术时间、住院天数、有创机械通气时间、抗生素使用时间、留置引流时间、术后重症监护病房入住天数是颅脑损伤术后院内感染的危险因素(P<0.05);Nomogram风险预测模型预测敏感度为92.36%,特异度为87.16%,具有良好的预测效能.结论 颅脑损伤术后院内感染与年龄、合并糖尿病等多种因素有关,需早发现、早预防,临床工作中应加强院内管理、增强医护人员业务水平,降低术后院内感染风险.

Abstract

Objective To observe the value of Nomogram model in predicting the risk of nosocomial infection after craniocerebral injury(CCI).Methods The clinical data of 240 patients with CCI treated from January 2021 to December 2022 were retrospectively analyzed,and nosocomial infections were analyzed to screen for influencing factors.A Nomogram model for predicting nosocomial infections was constructed by using R software,and the efficacy was evaluated by using receiv-er operating characteristic(ROC)curve.Results Among 240 patients with CCI,the incidence of nosocomial infection was 15.83%,and respiratory system infection was the highest.A total of 82 pathogenic bacteria were detected,mainly gram-positive bacteria.Age≥60 years,combined diabetes mellitus,open injury,Glasgow coma score<8 points,hypoproteine-mia,tracheotomy,duration of operation,length of hospital stay,duration of invasive mechanical ventilation,duration of anti-biotic use,indwelling time of drainage tube,and length of postoperative intensive care unit(ICU)stay were risk factors for nosocomial infection after CCI(P<0.05).The prediction sensitivity and specificity of the Nomogram risk prediction model were 92.36%and 87.16%respectively.Conclusion Nosocomial infection after CCI is related to various factors,including age and combined diabetes,which need early detection and prevention.In clinical practice,it is necessary to strengthen the hospital management,enhance the professional level of medical staff,and reduce the risk of postoperative nosocomial infec-tion.

关键词

颅脑损伤/术后/交叉感染/列线图/风险预测/年龄/抗生素使用时间/手术时间

Key words

Craniocerebral injury/Postoperation/Cross infection/Nomograms/Risk prediction/Age/Duration of antibiotic use/Duration of operation

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基金项目

保定市科技计划项目(2041ZF055)

出版年

2023
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
被引量1
参考文献量13
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