临床误诊误治2024,Vol.37Issue(1) :37-42.DOI:10.3969/j.issn.1002-3429.2024.01.008

误诊为色素痣的其他疾病140例分析

Analysis of 140 Patients with Other Diseases Misdiagnosed as Pigmented Nevus

郑建峰 孙振燕 牛多山 章婧 周奥 杨丽 朱文强
临床误诊误治2024,Vol.37Issue(1) :37-42.DOI:10.3969/j.issn.1002-3429.2024.01.008

误诊为色素痣的其他疾病140例分析

Analysis of 140 Patients with Other Diseases Misdiagnosed as Pigmented Nevus

郑建峰 1孙振燕 1牛多山 2章婧 1周奥 1杨丽 1朱文强1
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作者信息

  • 1. 242000 安徽宣城,宣城市人民医院皖南医学院附属宣城医院皮肤科
  • 2. 242000 安徽宣城,宣城市人民医院皖南医学院附属宣城医院病理科
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摘要

目的 分析其他相关疾病误诊为色素痣原因,并探讨防范措施,提高临床诊断水平.方法 回顾性分析2019 年1 月—2022 年12 月宣城市人民医院病理数据库中140 例初诊为色素痣,但经组织病理检查排除色素痣诊断的患者临床及组织病理资料.结果 误诊为皮肤色素痣140 例,男55 例,女 85 例,年龄(46.64±15.27)岁.皮损发生部位:头面颈部55 例,躯干部44 例,四肢22 例,手足部13 例,外阴6 例.经组织病理诊断为脂溢性角化病70 例,血管角皮瘤9 例,基底细胞癌8 例,皮肤纤维瘤7 例,角质层出血6 例,寻常疣4 例,表皮囊肿4 例,表皮鳞状上皮增生3 例,皮赘3 例,日光性角化病2 例,恶性黑素瘤 2 例,皮脂腺增生 2 例,毛发上皮瘤 2 例,汗孔瘤 2 例,钙化上皮瘤 2例,其他14 例.结论 多种疾病与色素痣临床特征相似,临床误诊率较高,综合临床特征、皮肤镜检查、皮肤组织病理检查等可明确诊断,提高诊断率.

Abstract

Objective To analyze causes of misdiagnosis of other related diseases as pigmented nevus,and to explore preventive measures so as to improve the clinical diagnosis.Methods A retrospective analysis was conducted on the clinical and pathological data of 140 cases which were selected from the pathological database of Xuancheng People's Hospital from Jan-uary 2019 to December 2022 and initially misdiagnosed as pigmented nevus before histopathological examination.Results Among the 140 cases clinically misdiagnosed as pigmented nevus,55 were males and 85 were females,aged 46.64±15.27 years.There were 55 cases of skin lesions on head,face and neck,44 cases on trunk,22 cases on limbs,13 cases on hands and feet,and 6 cases on vulva.Based on histopathological manifestation,70 cases were misdiagnosed with Seborrheic kerato-sis,9 with angiokeratoma,8 with basal-cell carcinoma,7 with cutaneous fibroma,6 with epidermis hemorrhage,4 with verru-ca vulgaris,4 with epidermoid cyst,3 with epidermal squamous cell hyperplasia,3 with soft fibroma,2 with actinic keratosis,2 with malignant melanoma,2 with sebaceous gland hyperplasia,2 with hair epithelioma,2 with syringoma,2 with calcified epithelioma and 14 with other skin diseases.Conclusion In clinical practice,many kinds of diseases are similar to pigmen-ted nevus and are more likely to be misdiagnosed.Combination of clinical features,dermatoscopic examination and skin histo-pathology can make definite diagnosis and improve the diagnostic rate.

关键词

脂溢性角化病/血管角皮瘤/基底细胞癌/皮肤纤维瘤/误诊/色素痣/皮肤镜/组织病理

Key words

Seborrheic keratosis/Angioceratoma/Basal cell carcinoma/Skin fibroma/Misdiagnosis/Pigmented ne-vus/Dermoscope/Histopathology

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出版年

2024
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
参考文献量24
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