临床误诊误治2024,Vol.37Issue(2) :106-111.DOI:10.3969/j.issn.1002-3429.2024.02.019

经穴体外反搏辅助治疗气阴两虚兼血瘀证心力衰竭伴失眠的效果

Effect of External Counterpulsation of Acupoints-assisted Conventional Treatment in Heart Failure Accompanied by Insomnia Caused by Syn-drome of Qi and Yin Deficiency Combined with Blood Stasis

兰泽毅 刘青敏 柳彩霞 胡学敬 夏梅华 彭冬燕
临床误诊误治2024,Vol.37Issue(2) :106-111.DOI:10.3969/j.issn.1002-3429.2024.02.019

经穴体外反搏辅助治疗气阴两虚兼血瘀证心力衰竭伴失眠的效果

Effect of External Counterpulsation of Acupoints-assisted Conventional Treatment in Heart Failure Accompanied by Insomnia Caused by Syn-drome of Qi and Yin Deficiency Combined with Blood Stasis

兰泽毅 1刘青敏 1柳彩霞 1胡学敬 1夏梅华 1彭冬燕1
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作者信息

  • 1. 053000 河北 衡水,衡水市中医医院心血管病科
  • 折叠

摘要

目的 探讨经穴体外反搏辅助治疗在气阴两虚兼血瘀证心力衰竭伴失眠患者中的应用效果.方法选取2021 年10 月—2022 年10 月收治的120 例气阴两虚兼血瘀证心力衰竭伴失眠患者,采用随机数字表法分为观察组和对照组,每组60 例,对照组采取常规治疗,观察组在上述常规治疗基础上配合经穴体外反搏治疗.比较2 组临床疗效、主要心血管不良事件(MACE)发生率、安全性,并比较治疗前后中医证候积分、心功能指标[左心室射血分数(LVEF)、每搏输出量(SV)、心排血量(CO)]、血清指标[N末端脑钠肽前体(NT-proBNP)、心肌型肌酸激酶同工酶(CK-MB)]、匹兹堡睡眠质量指数(PSQI)及心力衰竭生活质量量表(LHFQ)评分.结果 治疗14d后,观察组中医证候疗效总有效率及心功能疗效总有效率为 98.33%及 88.33%分别高于对照组的 83.33%及 73.33%(P<0.01,P<0.05);治疗后,观察组中医证候积分、PSQI量表各维度评分、LHFQ各领域评分低于对照组,LVEF、SV、CO水平高于对照组,血清NT-proBNP、CK-MB水平低于对照组(P<0.05);随访 6 个月,观察组MACE发生率 6.90%低于对照组的19.64%(P<0.05).2 组未见明显不良反应发生.结论 经穴体外反搏治疗将穴位刺激与体外反搏技术有机结合,可改善气阴两虚兼血瘀证心力衰竭伴失眠患者心功能,减轻临床症状,提升睡眠质量及生活质量,降低MACE发生率,调控血清NT-proBNP、CK-MB水平,疗效确切.

Abstract

Objective To investigate the effect of external counterpulsation of acupoint-assisted conventional treat-ment in patients with heart failure accompanied by insomnia caused by syndrome of Qi and Yin deficiency combined with blood stasis.Methods A total of 120 patients with heart failure and insomnia caused by syndrome of Qi and Yin deficiency com-bined with blood stasis treated from October 2021 to October 2022 were selected and divided into observation group(n =60)and control group(n =60)by random number table method.The control group received conventional treatment,and the ob-servation group was supplemented with external counterpulsation of acupoints on the basis of the above conventional treatment.The clinical efficacy,incidence of major cardiovascular adverse events(MACE)and safety of the two groups were compared.TCM syndrome score,cardiac function index[left ventricular ejection fraction(LVEF),stroke output(SV),cardiac volume(CO)],serum index[NT-terminal brain natriuretic peptide precursor(NT-proBNP),myocardial creatine kinase isoenzyme(CK-MB)],Pittsburgh Sleep quality index(PSQI)and Minnesota living with heart failure questionnaire(LHFQ)score be-fore and after treatment were compared.Results At 14 days after treatment,the total effective rate of TCM syndrome and cardiac function in the observation group were 98.33%and 88.33%,respectively,which were higher than those in the con-trol group(83.33%and 73.33%,P<0.01,P<0.05).After treatment,TCM syndrome scores,scores of various dimen-sions of PSQI scale and various fields of LHFQ scores in the observation group were lower than those in the control group,LVEF,SV and CO levels were higher than those in the control group,and serum NT-proBNP and CK-MB levels were lower than those in the control group(P<0.05).At 6 months after follow-up,the incidence of MACE in the observation group was 6.90%,which was lower than that in the control group(19.64%,P<0.05).No obvious adverse reactions were observed in the two groups.Conclusion The combination of acupoint stimulation and external counterpulsation technique can improve the heart function of patients with heart failure accompanied by insomnia caused by syndrome of Qi and Yin deficiency combined with blood stasis,relieve clinical symptoms,improve sleep quality and quality of life,reduce the incidence of MACE,and regulate the level of serum NT-proBNP and CK-MB,with definite effect.

关键词

心力衰竭/失眠/气阴两虚/血瘀/体外反搏/睡眠质量/生活质量/证候

Key words

Heart failure/Insomnia/Qi and Yin deficiency/Blood stasis/External counterpulsation/Sleep quality/Quality of life/Syndrome

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基金项目

河北省中医药局指导课题(2022619)

出版年

2024
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
参考文献量23
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