临床误诊误治2024,Vol.37Issue(3) :45-51.DOI:10.3969/j.issn.1002-3429.2024.03.011

Logistic回归与决策树模型对大面积急性岛叶梗死患者预后的预测价值

Prognostic Value of Logistic Regression and Decision Tree Model in Pa-tients with Large Area Acute Insular Infarction

包曼 梁菲菲 孙子慧
临床误诊误治2024,Vol.37Issue(3) :45-51.DOI:10.3969/j.issn.1002-3429.2024.03.011

Logistic回归与决策树模型对大面积急性岛叶梗死患者预后的预测价值

Prognostic Value of Logistic Regression and Decision Tree Model in Pa-tients with Large Area Acute Insular Infarction

包曼 1梁菲菲 2孙子慧1
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作者信息

  • 1. 075000 河北 张家口,张家口市第一医院全科医学科
  • 2. 075000 河北 张家口,张家口市第一医院老年病科
  • 折叠

摘要

目的 探讨Logistic回归模型和决策树模型对大面积急性岛叶梗死预后不良的预测价值.方法 回顾性分析2019 年1 月—2022 年12 月收治的大面积急性岛叶梗死100 例的临床资料,根据发病3 个月后改良Rankin量表分为预后良好组和预后不良组.统计2 组临床资料、实验室指标、疾病史等基线资料.构建Logistic回归模型、决策树模型分析预后不良影响因素.绘制受试者工作特征(ROC)曲线分析 2 种模型对预后不良的预测效能.结果 发病3 个月后失访3 例,预后不良发生率为 39.18%(38/97),预后良好率为 60.82%(59/97).Logistic回归分析显示,年龄、房颤、基线肌钙蛋白T(cTnT)、鸢尾素、闭锁蛋白(Occludin)是预后不良影响因素(P<0.01);决策树模型分析显示,年龄、房颤、基线cTnT及Occludin是预后不良影响因素;决策树模型预测预后不良的曲线下面积大于Logistic回归模型.结论 年龄、房颤、基线cTnT、Occludin是大面积急性岛叶梗死患者预后不良影响因素,基于上述因素构建Lo-gistic回归模型和决策树模型均具有良好应用价值,应结合2 种模型优点,为临床诊治提供新思路.

Abstract

Objective To explore the predictive value of Logistic regression model and decision tree model for poor prognosis of large area acute insular infarction.Methods Clinical data of 100 patients with large area acute insular infarction admitted from January 2019 to December 2022 were retrospectively analyzed.According to the modified Rankin scale at 3 months after the onset,they were divided into good prognosis group and poor prognosis group.Baseline data such as clinical data,laboratory indicators and disease history were collected.Logistic regression model and decision tree model were construc-ted to analyze the influencing factors of poor prognosis.Receiver operating characteristic(ROC)curve was drawn to analyze the predictive efficacy of the two models for poor prognosis.Results Three patients were lost to follow-up at 3 months after disease onset,and the incidence of poor prognosis was 39.18%(38/97),and good prognosis was 60.82%(59/97).Logis-tic regression analysis showed that age,atrial fibrillation,baseline troponin T(cTnT),irisin and Occludin were influencing factors of poor prognosis(P<0.01).Decision tree model analysis showed that age,atrial fibrillation,baseline cTnT and Oc-cludin were influencing factors of poor prognosis.The are under the ROC curve(AUC)of decision tree model in predicting poor prognosis was greater than that of Logistic regression model.Conclusion Age,atrial fibrillation,baseline cTnT,and Occludin are poor prognostic factors for patients with large area acute insular infarction,and the Logistic regression model and decision tree model constructed based on the above factors have good application value.Therefore,the advantages of the two models should be combined to provide a new idea for clinical diagnosis and treatment.

关键词

急性岛叶梗死/决策树模型/Logistic回归/临床转归/预测/心房颤动/肌钙蛋白T/影响因素

Key words

Acute insular infarction/Decision tree model/Logistic regression/Clinical outcome/Prediction/Atrial fibrillation/Troponin T/Influencing factor

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基金项目

河北省卫生健康委办公室医学科学研究课题(202111605)

张家口市科技局市级科技计划(2121136D)

出版年

2024
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
参考文献量37
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