Objective To explore the application effect of treatment management based on damage control theory(DCT)in the treatment of patients with liver and bile duct trauma.Methods The clinical data of 102 patients with liver and bile duct trauma treated from August 2022 to March 2023 were retrospectively analyzed.According to the clinical treatment plan,they were divided into the observation group(n =52)and the control group(n =50).The control group was treated with conventional emergency treatment,and the observation group was treated with treatment management based on DCT.The treatment-related indexes,complications and clinical outcomes,injury severity and oxidative stress indexes[myeloperoxidase(MPO),malondialdehyde(MDA),superoxide dismutase(SOD)]before and after intervention were observed in the two groups.Results The duration of operation,the first postoperative anal exhaust and length of hospital stay in the observation group were shorter than those in the control group,and the intraoperative blood loss was less than that in the control group(P<0.01).After intervention,the injury severity of observation group was lower than that of control group(P<0.05).Af-ter intervention,the serum MPO and MDA levels in the observation group were lower than those in the control group,while the serum SOD levels were higher than those in the control group(P<0.05).The incidence of multi-organ dysfunction syndrome and hemorrhagic shock in the observation group were 3.85%(3/52)and 1.92%(1/52),respectively,which were lower than those in the control group[18.00%(9/50)and 16.00%(8/50)],suggesting significant difference(P<0.05).Conclusion The treatment management based on DCT can reduce the stress and injury degree of patients with liver and bile duct trauma,accelerate the rehabilitation process,and improve the clinical outcome.
Damage control/Liver and bile duct trauma/Myeloperoxidase/Malondialdehyde/Superoxide dis-mutase/Multiple organ failure/Shock,hemorrhagic/Treatment management
维普
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