临床误诊误治2024,Vol.37Issue(3) :149-152.DOI:10.3969/j.issn.1002-3429.2024.03.029

脑小血管病总负荷与急性缺血性脑卒中的相关研究进展

Research Progress on the Correlation between Total Cerebral Small Vessel Disease Load and Acute Ischemic Stroke

龚晓晓 孙萍 伍国锋
临床误诊误治2024,Vol.37Issue(3) :149-152.DOI:10.3969/j.issn.1002-3429.2024.03.029

脑小血管病总负荷与急性缺血性脑卒中的相关研究进展

Research Progress on the Correlation between Total Cerebral Small Vessel Disease Load and Acute Ischemic Stroke

龚晓晓 1孙萍 2伍国锋3
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作者信息

  • 1. 550004 贵阳,贵州医科大学临床医学院
  • 2. 550005 贵阳,贵州医科大学附属金阳医院神经内科
  • 3. 550004 贵阳,贵州医科大学附属医院急诊神经科
  • 折叠

摘要

急性缺血性卒中是病死率、致残率较高的疾病之一,而静脉溶栓及血管内治疗是目前临床治疗该病的有效方法.脑小血管病的概念被提出后经过一系列研究发现,其与急性缺血性脑卒中治疗预后具有显著的相关性.特别是脑小血管病总负荷评分能够更好评估脑小血管病对大脑整体功能的影响情况,国内外已对其在急性缺血性脑卒中静脉溶栓及血管内治疗预后方面进行着各种层面的相关研究,旨在对急性缺血性卒中患者病情进展进行预判并提前干预,以降低患者致残率和病死率.本文着重对脑小血管病总负荷与急性缺血性脑卒中治疗预后的相关研究进行综述.

Abstract

Acute ischemic stroke(AIS)is one of the diseases with high mortality and disability rate,and intravenous thrombolysis and intravascular therapy are effective methods for the clinical treatment of this disease.After the concept of cere-bral small vessel disease(CSVD)was proposed,a series of studies have found that it has a significant correlation with the prognosis of AIS treatment.In particular,the total load score of CSVD can better assess the impact of CSVD on the overall brain function.At home and abroad,various levels of studies have been conducted on the prognosis of intravenous thrombolys-is and endovascular treatment of AIS,aiming at predicting progression of disease and intervening in advance for patients with AIS,so as to reduce the disability rate and mortality rate of patients.This review focuses on the correlation between the total load of CSVD and the prognosis of AIS.

关键词

脑小血管病/急性缺血性脑卒中/静脉溶栓/血管内治疗/脑白质高信号/血管周围间隙/脑微出血/脑萎缩

Key words

Cerebral small vessel disease/Acute ischemic stroke/Intravenous thrombolysis/Endovascular treat-ment/White matter hyperintensity/Perivascular space/Cerebral microbleed/Brain atrophy

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基金项目

贵州省卫生健康委科学技术基金(gzwjkj2020-1-012)

出版年

2024
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
参考文献量34
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