Objective To explore the clinical characteristics,causes of misdiagnosis and preventive measures of atypical pulmonary embolism in the elderly.Methods Clinical data of 10 elderly patients with atypical pulmonary embolism admitted and misdiagnosed as pneumonia in our hospital from January 2018 to January 2023 were retrospectively analyzed.Re-sults The main clinical manifestations of the 10 patients were chest pain,shortness of breath,fever and dyspnea,among which dry rales could be heard in the lungs of 3 patients,and wet rales could be heard in the lungs of 3 patients on ausculta-tion.X-ray chest radiographs and CT examinations of all the patients suggested lung infections,and they were all misdiagnosed with pneumonia.The duration of misdiagnosis was 3-9 d.After corresponding treatment for misdiagnosed disease,the condi-tion of 10 patients was repeated or continued to aggravate.Atypical pulmonary embolism was confirmed by CT pulmonary arte-riography,and all patients were discharged from the hospital with a good condition after being given anticoagulant and throm-bolytic treatments.Conclusion The clinical manifestations of elderly patients with atypical pulmonary embolism are not spe-cific,most of them do not have typical symptoms at the early stage of the disease,and the clinical symptoms and imaging data have a high degree of overlap with those of pneumonia,which is,therefore,more likely to be misdiagnosed.For patients with chest tightness,dyspnea and ineffective treatment,it is necessary to screen for atypical pulmonary embolism before confirming the diagnosis of the patient's condition,to minimize the misdiagnosis and misdiagnosis.