Objective To analyze the causes and preventive measures of misdiagnosis of heart failure with preserved ejection fraction(HFpEF)as chronic bronchitis in the elderly.Methods The clinical data of 7 elderly HFpEF patients who were initially misdiagnosed as chronic bronchitis from October 2019 to April 2021 were retrospectively analyzed.Results The main symptoms of 7 patients were cough,phlegm,fatigue and shortness of breath.White blood cell count and neutrophil count were slightly increased in 3 patients.Chest X-ray examination showed thickening and disordered lung texture in 7 patients,and slightly larger heart shadow in 2 patients.All the 7 patients were diagnosed with chronic bronchitis(acute attack)at first,and were treated with empirical anti-infection,antitussive and expectorant treatment in other hospitals for 1-2 weeks,with no obvious remission.After admission,the condition was analyzed comprehensively,and electrocardiogram(ECG)revealed my-ocardial ischemia,and left ventricular hypertrophy with strain.Echocardiography showed that the left ventricular diastolic function was abnormal,and left ventricular ejection fraction was normal.The diagnosis was HFpEF,and the duration of misdi-agnosis was 1-3 months.After diagnosis,the symptoms were obviously alleviated or disappeared after treatment to improve left ventricular diastolic function,reduce blood pressure and relieve pulmonary congestion.Conclusion There are many basic diseases in the elderly,and misdiagnosis is often made when the symptoms of respiratory complications are severe and cover up the symptoms of heart failure.Strengthening the understanding of HFpEF in the elderly,inquiring the medical history in de-tail,raising the vigilance of the disease,carefully differentiating diagnosis,and timely performing electrocardiogram,echocar-diography and comprehensive analysis of the disease are conducive to reducing or avoiding misdiagnosis and mistreatment.