临床误诊误治2024,Vol.37Issue(5) :14-18.DOI:10.3969/j.issn.1002-3429.2024.05.004

胰腺浆液性囊腺瘤误诊病例的MSCT影像特征与病理分析

Analysis of MSCT Imaging Features and Pathological Features of Misdiag-nosed Pancreatic Serous Cystadenoma

王朋 李云 王晓艳 周静 姬广海
临床误诊误治2024,Vol.37Issue(5) :14-18.DOI:10.3969/j.issn.1002-3429.2024.05.004

胰腺浆液性囊腺瘤误诊病例的MSCT影像特征与病理分析

Analysis of MSCT Imaging Features and Pathological Features of Misdiag-nosed Pancreatic Serous Cystadenoma

王朋 1李云 1王晓艳 2周静 3姬广海1
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作者信息

  • 1. 434000 湖北荆州,长江大学附属第一医院放射科
  • 2. 434000 湖北荆州,长江大学附属第一医院病理科
  • 3. 434000 湖北荆州,长江大学附属第一医院麻醉科
  • 折叠

摘要

目的 探讨胰腺浆液性囊腺瘤(PSC)的影像特征及病理基础,分析误诊原因,总结防范措施.方法 回顾性分析2017-2023 年经手术病理证实为PSC且术前多层螺旋CT误诊为其他病变 22 例的临床资料及CT影像特征,并与病理HE染色对照分析.结果 本组22 例中因腹痛就诊 7 例,恶心呕吐就诊 1 例,其余 14 例均为体检发现,其中微囊型10 例,大囊型8 例,混合型3 例,实质型1 例;8 例位于胰腺头颈部,14 例位于体尾部;分叶状13 例,中央瘢痕2 例,钙化5 例,上游胰管扩张5 例;增强后明显强化 3 例,中度强化 5 例,轻度强化 6 例,无强化 8 例.13 例PSC呈分叶状轮廓、边界清晰、呈蜂窝或多囊状结构、与胰管不相通,2 例PSC可见内部纤维瘢痕,5 例可见钙化等特征性影像表现.误诊为黏液性囊腺瘤和神经内分泌瘤各5 例,实性假乳头状瘤4 例,未定性3 例,假性囊肿2 例,潴留囊肿、胰腺导管内乳头状瘤、胰腺癌各1 例.误诊时间 7~180 d.均手术治疗并经术后病理学检查确诊.随访均无复发.结论 不同类型PSC影像表现存在一定差异,但同时存在一些共同影像特征,对于非典型病例,CT诊断困难,误诊率高,需提高对于本病的认知,同时密切结合临床病史,可提高其诊断准确率.

Abstract

Objective To investigate the imaging features and pathological basis of pancreatic serous cystadenoma(PSC),to analyze the causes of misdiagnosis,and to summarize the preventive measures.Methods The clinical data and CT image features of 22 patients with PSC confirmed by surgical pathology and misdiagnosed as other lesions by multi-slice spi-ral CT before surgery from 2017 to 2023 were retrospectively analyzed,and compared with pathological HE staining.Methods Among the 22 patients,7 presented with abdominal pain,1 presented with nausea and vomiting,and the other 14 patients were accidentally found during physical examination,including 10 cases of microcystic type,8 cases of oligocystic type,3 ca-ses of mixed type,and 1 case of parenchymal type.The lesion was located in the head and neck of the pancreas in 8 patients and in the tail of the body in 14 patients,including lobulation in 13 patients,central scar in 2 patients,calcification in 5 pa-tients,and upper pancreatic duct dilatation in 5 patients.After enhancement,3 cases were significantly strengthened,5 cases were moderately strengthened,6 cases were mildly strengthened,and 8 cases were not strengthened.In 13 cases,PSC showed lobulated contour,clear boundary,honeycomb or polycystic structure,and no communication with pancreatic duct.Two pa-tients with PSC showed internal fiber scar,and 5 patients showed calcification and other characteristic image manifestations.There was misdiagnosis as mucinous cystadenoma in 5 patients,neuroendocrine tumor in 5 patients,solid pseudopapilloma in 4 patients,indeterminable tumor in 3 patients,pseudocyst in 2 patients,retention cyst in 1 patients,intraductal papilloma in pancreas in 1 patient,and pancreatic cancer in 1 patient.Misdiagnosis lasted from 7 to 180 d.All patients were treated with surgery and confirmed by postoperative pathological examination.There was no recurrence during follow-up.Conclusion There are several differences in the imaging manifestations of different types of PSC,but in the meantime,there are some com-mon imaging characteristics.For atypical cases,diagnosis using CT is difficult and the misdiagnosis rate is high,so it is nec-essary to improve the understanding of the disease and closely combine the clinical history to improve the diagnostic accuracy.

关键词

囊腺瘤,浆液/误诊/囊腺瘤,黏液/神经内分泌瘤/实性假乳头状瘤/胰腺导管内乳头状瘤/胰腺肿瘤

Key words

Cystadenoma,serous/Misdiagnosis/Cystadenoma,mucinous/Neuroendocrine tumors/Solid pseudo-papilloma/Intraductal papilloma of pancreas/Pancreatic Neoplasms

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出版年

2024
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
参考文献量20
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