摘要
目的 探讨六字诀养生功结合刮痧疗法对慢性阻塞性肺疾病(COPD)稳定期患者心肺功能、活动耐力的影响.方法 选取 2021 年 5 月—2023 年 6 月就诊的 158 例COPD稳定期为研究对象,按照随机数字表法分为 2组,各79 例.对照组给予常规西药治疗,观察组在对照组基础上给予六字诀养生功结合刮痧疗法治疗,疗程均为3 个月.比较2 组临床疗效、不良反应,以及治疗前后中医证候积分、肺功能[呼气峰值流速(PEF)、第1 秒用力呼气容积占预计值的百分比(FEV1%)、用力肺活量(FVC)]、活动耐力[6 min步行距离(6MWD)、30s坐立次数]、血清免疫-炎性指标[降钙素原(PCT)、白细胞介素-8(IL-8)、免疫球蛋白A(IgA)、IgG]、圣乔治呼吸问卷(SGRQ)评分.结果 观察组总有效率92.41%(73/79)高于对照组81.01%(64/79)(P＜0.05).治疗1、3 个月后,观察组PCT、IL-8、SGRQ评分、各中医证候积分及总分均低于对照组,PEF、FEV1%、FVC、IgA、IgG、6MWD及30s坐立次数均高于对照组(P＜0.05).不良反应总发生率2 组比较差异无统计学意义(P＞0.05).结论 六字诀养生功结合刮痧疗法治疗COPD稳定期患者效果显著,可提升患者肺功能、减轻临床症状、增强活动耐力、抑制炎症反应、提升免疫功能,从而有效改善预后,且安全性高.
Abstract
Objective To investigate the effects of the six-character exercise regimen combined with scraping therapy on cardiopulmonary function and activity tolerance in patients with stable chronic obstructive pulmonary disease(COPD).Methods A total of 158 patients with stable COPD who were treated from May 2021 to June 2023 were selected as the re-search subjects and divided into two groups,with 79 cases in each group according to random number table method.The con-trol group was given conventional western medicine,while the observation group was given the combination of six-character ex-ercise regimen and scraping therapy on the basis of the control group,with a course of treatment for three months.The clinical efficacy and adverse reactions of the two groups,as well as the TCM syndrome scores,pulmonary function[peak expiratory flow rate(PEF),percentage of forced expiratory volume in one second(FEV1%),forced vital capacity(FVC)],activity tolerance[6-minute walking distance(6MWD),number of sit-ups in 30 seconds],serum immune-inflammatory indicators[procalcitonin(PCT),interleukin-8(IL-8),immunoglobulin A(IgA),IgG],and St.George's Respiratory Questionnaire(SGRQ)scores before and after treatment were compared.Results The total effective rate in the observation group was 92.41%(73/79),which was higher than that in the control group(81.01%,64/79)(P＜0.05).At 1 and 3 months after treatment,the PCT,IL-8,SGRQ score,and TCM syndrome scores and total scores in the observation group were lower than those in the control group,while PEF,FEV1%,FVC,IgA,IgG,6MWD,and number of sit-ups in 30 seconds were higher than those in the control group(P＜0.05).There was no significant difference in the total incidence of adverse reactions be-tween the two groups(P＞0.05).Conclusion The combination of the six-character exercise regimen and scraping therapy has significant effects in the treatment of patients with stable COPD,which can improve their pulmonary function,alleviate clinical symptoms,enhance activity tolerance,inhibit inflammatory reactions,and enhance immune function,thereby effec-tively improving prognosis and providing high safety.
基金项目
浦东新区卫生健康委重要薄弱学科建设项目(PWZbr2022-07)
维普
万方数据