CTCA定量参数对冠心病患者短期病死预测价值
Predictive Value of Quantitative Parameters of CTCA for Short-term Mor-tality in Patients with Coronary Heart Disease
董小波 1张仲慧 1郭庆乐 2焦鹏飞1
作者信息
- 1. 063000 河北唐山,开滦总医院核医学科
- 2. 063000 河北唐山,开滦总医院CT室
- 折叠
摘要
目的 探讨CT冠状动脉造影(CTCA)定量参数对冠心病患者短期病死预测价值.方法 选取2021 年3 月—2023 年3 月收治的冠心病200 例,比较不同冠状动脉病变程度冠心病患者CTCA定量参数(动脉阻力指数、总斑块负荷和斑块最小密度CT值),分析CTCA定量参数与冠心病患者冠状动脉病变程度相关性,探讨术后1 年冠心病患者病死情况,分析CTCA定量参数与冠心病患者短期病死风险关联性,评价CTCA定量参数对冠心病患者短期病死预测价值.结果 不同冠状动脉病变程度冠心病患者动脉阻力指数、总斑块负荷逐渐升高,斑块最小密度CT值逐渐降低(P＜0.05).冠心病患者动脉阻力指数、总斑块负荷与疾病类型、病变支数及狭窄程度呈正相关,斑块最小密度CT值与疾病类型、病变支数及狭窄程度呈负相关(P＜0.05).冠心病200 例中39 例(19.50%)术后1 年病死.动脉阻力指数、总斑块负荷和斑块最小密度CT值与冠心病患者短期病死有关(P＜0.01).对冠心病患者短期病死预测的受试者工作特征曲线下面积动脉阻力指数、总斑块负荷和斑块最小密度 CT值三者联合明显高于单独预测(P＜0.05).结论 CTCA定量参数与冠心病患者冠状动脉病变程度密切相关,且联合各参数预测冠心病患者短期病死价值较高.
Abstract
Objective To investigate the value of quantitative parameters of CT coronary angiography(CTCA)in predicting short-term mortality in patients with coronary heart disease(CHD).Methods In total,200 patients with CHD ad-mitted from March 2021 to March 2023 were selected,and CTCA quantitative parameters(arterial resistance index,total plaque load and minimum CT density of plaques)of CHD patients with different degrees of coronary artery disease(CAD)were compared,and the correlation between CTCA quantitative parameters and the degree of CAD was analyzed.The 1-year postoperative mortality of patients with CHD was analyzed,the correlation between CTCA quantitative parameters and risk of short-term mortality in patients with CHD was explored,and the predictive value of CTCA quantitative parameters for short-term mortality in patients with CHD was evaluated.Results The arterial resistance index and total plaque load of CHD patients with different degrees of CAD increased gradually,and the minimum plaque density decreased gradually(P＜0.05).In CHD patients,the arterial resistance index and total plaque load were positively correlated with disease type,number of lesions and degree of stenosis,while the minimum CT density of plaques was negatively correlated with disease type,number of lesions and degree of stenosis(P＜0.05).Among200 CHDpatients,39(19.50%)died at one year after surgery.Arterial resistance in-dex,total plaque load and minimum CT density of plaques were associated with the risk of short-term mortality in patients with CHD(P＜0.01).The area under the receiver operating characteristic curve of combined detection of arterial resistance index,total plaque load and minimum CT density of plaques was significantly higher than that of individual indicator in prediction(P＜0.05).Conclusion CTCA quantitative parameters are closely related to the degree of CAD in patients with CHD,and the val-ue of CTCA parameters in combination is higher in predicting the risk of short-term mortality in patients with CHD.
关键词
冠心病/CT冠状动脉造影/定量参数/动脉阻力指数/总斑块负荷/斑块最小密度CT值/冠状动脉病变程度/病死Key words
Coronary heart disease/CT coronary angiography/Quantitative parameters/Arterial resistance index/Total plaque load/Minimum density CT value of plaque/Severity of coronary artery disease/Died of illness引用本文复制引用
基金项目
河北省医学科学研究项目(20221586)
出版年
2024
国家科技期刊平台
NSTL
万方数据