Objective To analyze the diagnostic accuracy of multimodal ultrasound combined with fine needle aspira-tion(FNA)for thyroid microcarcinoma(TMC)≤5 mm in diameter.Methods The clinical data of 120 patients(132 nod-ules)with thyroid micronodules≤5 mm confirmed by surgery and pathology who underwent multimodal ultrasound[two-di-mensional(2D)ultrasound,contra-ultrasound,ultrasonic elastography(UE)]combined with FNA from September 2019 to March 2021 were retrospectively analyzed.The consistency of multimodal ultrasound,FNA and combined detection with path-ological diagnosis was analyzed,and the diagnostic value of single and combined detection was analyzed by receiver operating characteristic(ROC)curve.Results Pathological analysis of 132 thyroid micronodules≤5 mm in diameter showed 36 be-nign nodules and 96 TMC nodules.Compared with the pathological results,the diagnostic coincidence rate of 2-D ultrasound was85.60%(113/132),and Kappa value was0.646.The diagnostic coincidence rate of contra-ultrasound was 90.15%(119/132),and Kappa value was0.758.The diagnostic coincidence rate of UE was90.15%(119/132),and Kappa value was 0.754.The diagnostic coincidence rate of multimodal ultrasound was 90.91%(120/132),and Kappa value was 0.771.The diagnostic coincidence rate of FNA was 92.42%(122/132),and Kappa value was 0.806.The diagnostic coincidence rate of multimodal ultrasound combined with FNA was 94.70%(125/132),and the Kappa value was 0.860.ROC curve analysis showed that there was no difference in the area under ROC curve(AUC)of the single diagnosis between multimodal ultrasound and FNA(P＞0.05).The AUC of the combined diagnosis of TMC by multimodal ultrasound and FNA was greater than that by single diagnosis(P＜0.05).Conclusion Both multimodal ultrasound and FNA have good clinical diagnostic value for TMC≤5 mm in diameter,and the combination of the two can improve the accuracy of clinical diagnosis.
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