阻塞性睡眠呼吸暂停低通气综合征干预对合并视网膜分支静脉阻塞的疗效观察
Observation of Therapeutic Effect of Intervention for Obstructive Sleep Apnea Hypopnea Syndrome on Combined Branch Retinal Vein Obstruction
崔明霞 1树玲博 1李楠 2段颖 1张阳 1刘晓哲 3任国英4
作者信息
- 1. 053000 河北衡水,衡水市第四人民医院眼科
- 2. 053000 河北衡水,衡水市第四人民医院超声科
- 3. 253899 河北故城,故城县医院眼科
- 4. 053000 河北衡水,衡水市第四人民医院耳鼻咽喉头颈外科
- 折叠
摘要
目的 探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)干预对合并视网膜分支静脉阻塞(BRVO)疗效的影响.方法 选取2020年6月至2021年12月收治的202例BRVO合并OSAHS,采用随机数字表法分为观察组101例和对照组101例,对照组给予BRVO规范治疗,观察组给予BRVO规范治疗与生活方式干预(饮食指导及体位疗法),统计比较2组入组时及入组后1个月、6个月、1年、1.5年夜间平均动脉血氧饱和度(MSaO2)、最低动脉血氧饱和度(LSaO2)、氧减指数(ODI)及最佳矫正视力、黄斑中心凹视网膜厚度(CRT)和视网膜中央动脉(CRA)舒张末期血流速度(EDV)、收缩期峰值流速(PSV),以及入组后1.5年内2组并发症累计发生率和累计实施手术率.结果 观察组并发症累计发生率(13.54%)、累计实施手术率(8.33%)较对照组(26.97%、19.10%)低(P＜0.05).入组后1个月、6个月、1年、1.5年观察组夜间MSaO2、LSaO2及CRA的PSV、EDV均高于对照组,夜间ODI、最佳矫正视力、CRT均低于对照组(P＜0.05,P＜0.01).结论 在BRVO治疗的同时给予OSAHS干预有利于促进BRVO合并OSAHS病情恢复.
Abstract
Objective To investigate the effect of intervention for obstructive sleep apnea hypopnea syndrome(OSAHS)on the efficacy of combined branch retinal vein obstruction(BRVO).Methods A total of 202 patients with BRVO complicated with OSAHS treated from June 2020 to December 2021 were selected and divided into observation group(n=101)and control group(n=101)by random number table method.The control group was given BRVO standard treatment,and the observation group was given BRVO standard treatment and lifestyle intervention(dietary guidance and posture therapy).The mean arterial oxygen saturation(MSaO2)during night time,lowest arterial oxygen saturation(LSaO2),oxygen desaturation index(ODI),best corrected visual acuity(BCVA),macular foveal retinal thickness(CRT),central retinal artery(CRA)end-diastolic blood flow velocity(EDV),peak systolic flow velocity(PSV)between the two groups at the time of enrollment and at 1 month,6 months,1 year and 1.5 years after enrollment,as well as the cumulative incidence of complications and the cumula-tive rate of operation performed in the two groups within 1.5 years after enrollment,were statistically compared.Results The cumulative incidence of complication(13.54%)and cumulative rate of operation(8.33%)in the observation group were lower than those in the control group(26.97%,19.10%)(P<0.05).At 1 month,6 months,1 year and 1.5 years after admission,PSV and EDV of MSaO2,LSaO2 during night time and CRA in observation group were higher than those in control group,while ODI during night time,BCVA and CRT were lower than those in control group(P<0.05,P<0.01).Conclusion Intervention for OSAHS during BRVO treatment can promote the recovery of BRVO combined with OSAHS.
关键词
视网膜分支静脉阻塞/阻塞性睡眠呼吸暂停低通气综合征/动脉血氧饱和度/氧减指数/视力/黄斑中心凹视网膜厚度/舒张末期血流速度/并发症Key words
Brain retinal vein occlusion/Obstructive sleep apnea hypopnea syndrome/Arterial oxygen saturation/Oxygen desaturation index/Visual acuity/Macular foveal retinal thickness/End-diastolic blood flow velocity/Complication引用本文复制引用
基金项目
衡水市重点研发计划项目(2023014067Z)
出版年
2024
国家科技期刊平台
NSTL
万方数据