临床误诊误治2024,Vol.37Issue(12) :14-16.DOI:10.3969/j.issn.1002-3429.2024.12.003

脉络膜恶性黑色素瘤误诊误治分析

Analysis of Misdiagnosis and Mistreatment of Malignant Choroi-dal Melanoma

魏美慧 张志强 左晶 施炜
临床误诊误治2024,Vol.37Issue(12) :14-16.DOI:10.3969/j.issn.1002-3429.2024.12.003

脉络膜恶性黑色素瘤误诊误治分析

Analysis of Misdiagnosis and Mistreatment of Malignant Choroi-dal Melanoma

魏美慧 1张志强 1左晶 1施炜1
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作者信息

  • 1. 210029 南京,南京中医药大学附属医院眼科
  • 折叠

摘要

目的 探讨以玻璃体积血为首发症状的脉络膜恶性黑色素瘤(CM)临床特征、误诊原因及防范措施.方法 回顾性分析2023年12月收治的脉络膜黑色素瘤1例的临床资料.结果 该例因双眼视物模糊,于外院诊断为玻璃体积血行玻璃体切割联合白内障超声乳化人工晶体植入术后7个月,术后视物不见,伴眼胀痛,加重7d入院,考虑为继发性青光眼,完善术前检查后行"左眼球摘除术",术中发现色素块,标本送病理检查确诊恶性黑色素瘤,行PET-CT全身断层显像排除其他部位原发肿瘤或转移病灶.行"左眼眼眶内容物清除术",术后予对症处理.随访半年未见明显异常.结论 以玻璃体积血为首发症状的CM易误诊,医生在接诊此类病例时,应采取综合性的诊断策略,必要时活检,以降低误诊风险.

Abstract

Objective To investigate the clinical features,causes of misdiagnosis and preventive measures of malig-nant choroidal melanoma(CM)with vitreous hemorrhage as the initial symptom.Methods The clinical data of 1 patient with CM misdiagnosed and mistreated in December 2023 were retrospectively analyzed.Results Due to blurred vision in both eyes for several days,the patient was diagnosed as vitreous hemorrhage and underwent vitrectomy combined with phacoemulsifica-tion and intraocular lens implantation for cataracts 7 months afterwards.After surgery,the patient was admitted to the hospital with no vision after surgery,accompanied by eye distension and aggravation for 7 d.The patient was considered to have second-ary glaucoma.After completing preoperative examination,a left eye enucleation was performed.Pigment clumping was found during the surgery,and the specimen was sent for pathological examination to confirm malignant melanoma.Whole body PET-CT tomography was performed to exclude primary tumors or metastases at other sites.Removal of orbital contents of the left eye was performed and symptomatic treatment was given after surgery.No significant abnormality was found at 6-month follow-up.Conclusion CM with vitreous hemorrhage as the initial symptom is more likely to be misdiagnosed.For those patients,attend-ing physicians should adopt comprehensive diagnostic strategy and perform biopsy if necessary to reduce the risk of misdiagnosis.

关键词

脉络膜肿瘤/黑色素瘤/误诊/玻璃体积血/青光眼/正电子发射断层扫描及电脑断层扫描

Key words

Choroid neoplasms/Melanoma/Misdiagnosis/Vitreous hemorrhage/Glaucoma/Positron-emission to-mography and computed tomography

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出版年

2024
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
参考文献量4
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