临床误诊误治2024,Vol.37Issue(16) :6-9,15.DOI:10.3969/j.issn.1002-3429.2024.16.002

口腔颌面部结核临床误诊分析

Analysis of Clinical Misdiagnosis of Oral and Maxillofacial Tuberculosis

范宗尚 马丽爽 付明晨 黄涛
临床误诊误治2024,Vol.37Issue(16) :6-9,15.DOI:10.3969/j.issn.1002-3429.2024.16.002

口腔颌面部结核临床误诊分析

Analysis of Clinical Misdiagnosis of Oral and Maxillofacial Tuberculosis

范宗尚 1马丽爽 1付明晨 2黄涛1
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作者信息

  • 1. 053000 河北衡水,衡水市人民医院口腔科
  • 2. 053000 河北衡水,衡水市人民医院手术室
  • 折叠

摘要

目的 分析口腔颌面部结核临床特点、误诊原因及防范措施.方法 回顾分析 2019 年 2 月至 2023 年5 月收治2 例曾误诊的口腔颌面部结核患者的临床资料.结果 1 例张口受限(张口度<3cm),左侧口腔黏膜可见破溃,边缘呈虫噬状,表面覆盖脓性分泌物,外院病理检查提示慢性炎症,予抗感染治疗 1 周无效,入院后经胸部X线、CT检查,并再次取病变组织活检,确诊为口腔颌面部结核.1 例舌背右侧见0.8 cm×1.0 cm溃疡,边界清晰,呈弹坑状,边缘呈鼠咬状,结合患者症状表现,初步诊断为创伤性口腔溃疡,给予抗感染治疗无效,进一步经胸部X线、结核抗体、病理活检及抗酸染色检查,确诊为口腔颌面部结核.误诊时间分别为12d和7 个月.2 例确诊后均行抗结核治疗,6 个月后复诊显示口腔糜烂黏膜、舌黏膜溃疡均愈合,预后较好.结论 口腔颌面部结核症状常不典型,误诊率较高,确诊主要依靠病理学检查,复杂病例需多种方法综合分析,并仔细询问病史,查找其他部位结核病灶,及早行病理活检,必要时可试验性抗结核治疗,以提高本病诊断率.

Abstract

Objective To analyze the clinical characteristics,causes of misdiagnosis and preventive measures of oral and maxillofacial tuberculosis.Methods The clinical data of 2 patients with misdiagnosed oral and maxillofacial tuberculosis treated from February 2019 to May 2023 were retrospectively analyzed.Results One patient had restricted mouth opening(mouth opening<3 cm),and the left mucosa was observed to be ulcerated with a worm like edge and covered with purulent secretions.Pathological examination in other hospitals indicated chronic inflammation,and anti-infection-resistant treatment was ineffective for 1 week.Chest X-ray and CT examinations were conducted in our hospital after admission,followed by biop-sy of the lesion tissue,which was confirmed as oral and maxillofacial tuberculosis.Due to a 0.8 cm×1.0 cm ulcer seen on the right side of the back of the tongue with a clear boundary resembling a bullet hole and mouse-bite edges,the patient was initially diagnosed as a traumatic oral ulcer combined with the symptoms of the patient,and anti-infection treatment was inef-fective.Further examination by chest X-ray,tuberculosis antibody,pathological biopsy and acid-fast staining confirmed the di-agnosis of oral and maxillofacial tuberculosis.The misdiagnosis lasted 12 d and 7 months,respectively.Both patients received anti-tuberculosis treatment after diagnosis.After 6 months,the oral erosion mucosa and tongue mucosa ulcer were healed,and the prognosis was good.Conclusion The symptoms of oral and maxillofacial tuberculosis are often atypical,and the misdiag-nosis rate is high.The diagnosis mainly depends on pathological examination.Complex cases should be comprehensively ana-lyzed by various methods,the medical history should be carefully consulted,tuberculosis lesions in other areas should be found,and pathological biopsy should be performed as soon as possible.In addition,experimental anti-tuberculosis therapy can be performed if necessary,so as to improve the diagnosis rate of the disease.

关键词

结核/口腔颌面部/误诊/慢性炎症/口腔溃疡/病理检查/鉴别诊断/抗酸染色

Key words

Tuberculosis/Oral and maxillofacial/Misdiagnosis/Chronic inflammation/Oral ulcer/Pathological ex-amination/Differential diagnosis/Anti-acid staining

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基金项目

衡水市科技计划项目(2023014029Z)

出版年

2024
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
参考文献量20
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