Objective To analyze the causes of misdiagnosis of early knee osteoarthritis(KOA)to improve the diag-nostic accuracy of the disease.Methods The clinical data of 3 patients with KOA who were initially diagnosed with other dis-eases from February 2021 to April 2022 were retrospectively analyzed.Results One patient presented with morning stiffness and swelling of right knee joint,and was diagnosed with rheumatoid arthritis.The misdiagnosis lasted 11 d.Further ultrasound examination showed no synovial hyperplasia in the joint,but there was obvious cartilage wear.MRI showed degenerative chan-ges in the articular cartilage,and KOA was finally diagnosed;the patient recovered well after symptomatic treatment to control pain and inflammation.One patient presented with sudden knee joint swelling and pain at initial hospital visit.After X-ray ex-amination,the initial diagnosis was meniscus injury,and the misdiagnosis lasted 9 d.The symptoms did not improve after treatment with oral NSAID,and MRI showed degeneration of the articular cartilage and osteophyte formation,followed by a de-finitive diagnosis of KOA.The symptoms improved significantly after physical therapy and arthroscopic surgery.One patient was diagnosed with gout due to redness,swelling,warmth and pain in the right knee joint,with a history of gout.The initial diagnosis was gout,and the misdiagnosis lasted 10 d.The condition did not improve after receiving relevant treatment.Further ultrasound examination showed no urate crystals in the joints,but the degeneration of the articular cartilage became obvious,and KOA was finally diagnosed.Physical therapy and joint protection measures were used,and the symptoms gradually eased.Conclusion Due to its similar symptoms to other joint diseases,KOA is prone to misdiagnosis.By increasing the alertness of doctors,improving the diagnostic process,and strengthening patient education,it can significantly reduce misdiagnosis,im-prove diagnostic accuracy and treatment effectiveness,and improve patient prognosis.
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