Objective To analyze the risk probability distribution of heart failure in patients with subclinical hyperthy-roidism(SH),in order to reduce the risk of patients with SH complicated with heart failure and assist clinical intervention.Methods A total of 133 patients with SH admitted from May 2021 to January 2024 were selected as the research subjects,and the patients were divided into the occurrence group(n=49)and the non-occurrence group(n=84)according to the criteria for judging heart failure.The general data and laboratory indicators of the two groups were compared,and the influencing factors of heart failure were screened by multivariate Logistic regression analysis.The differences in the distribution characteristics of influ-encing factors between the high-risk group and the low-risk group of heart failure in patients with SH were compared by latent class analysis(LCA)model.Results Compared with the non-occurrence group,the proportion of angiotensin converting en-zyme inhibitors/angiotensin receptor blockers and the proportion of underlying diseases in the occurrence group were significantly increased,and the course of SH was significantly prolonged(P＜0.05).Compared with the non-occurrence group,the levels of total cholesterol,low-density lipoprotein cholesterol,tumor necrosis factor(TNF)and B-type natriuretic peptide(BNP)in the occurrence group were significantly increased,while the levels of transcutaneous oxygen saturation,high-density lipoprotein cho-lesterol(HDL-C)and insulin-like growth factor-Ⅱwere significantly decreased(P＜0.01).The course of SH,combined under-lying disease,HDL-C,TNF and BNP were the independent influencing factors of heart failure in SH patients(P＜0.05,P＜0.01).Compared with the low-risk group of SH complicated with heart failure,the ＂high-risk distribution＂ in the high-risk group was higher,while the＂low-risk distribution＂ was lower(P＜0.05).Conclusion The probability of developing heart fail-ure in the high-risk group of subclinical SH complicated with heart failure was significantly higher than that in the low-risk group.The distribution characteristics of influencing factors in high-and low-risk groups of complicated heart failure were different.
维普
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