Objective To compare and analyze the CT features of occult small pancreatic cancer with acute pancreati-tis(SPC-AP)with acute pancreatitis as the initial symptom and simple acute pancreatitis(S-AP).Methods A total of 34 patients with acute pancreatitis as the initial symptom and confirmed as SPC-AP by pathological examination were collected from January 2014 to August 2023,and 68 patients diagnosed with S-AP after more than 1 year of follow-up were randomly se-lected,all of whom underwent phaseⅢ CT enhanced scanning of pancreas at the time of initial diagnosis.The differences of clinical data and CT features between the two groups were compared and analyzed.Results The age of SPC-AP group was higher than that of S-AP group(P<0.05).The incidence of CT truncation artifacts in arterial phase enhancement of pancre-atic parenchyma,localized low enhancement area,main pancreatic duct dilation and truncation in SPC-AP group were higher than those in S-AP group(P<0.01).The incidence of peripheral vascular involvement,collateral circulation formation and clear structure in SPC-AP group was higher than that in S-AP group,while the incidence of pancreatic enlargement and local fluid accumulation around the pancreas was lower than that in the S-AP group(P<0.01).There was a significant difference in the location of the prerenal fascia thickening and the diameter of the common bile duct between the two groups(P<0.05,P<0.01).There was no significant difference in the display rates of common bile duct dilation,prerenal fascia thickening and peripancreatic lymph nodes between the two groups(P>0.05).Conclusion In adults with unexplained mild pancreatitis and left prerenal fascia thickening,when multi-phase CT enhanced scan shows signs of truncation artifacts in arterial phase en-hancement of pancreatic parenchyma,localized low enhancement,main pancreatic duct dilation and truncation,occult SPC-AP should be suspected.