Objective To investigate the causes and preventive measures of misdiagnosis of ankylosing spondylitis(AS)as Haglund syndrome.Methods The clinical data of 2 patients with AS who had been misdiagnosed as Haglund syn-drome from 2018 to 2024 were retrospectively analyzed.Results Both patients presented with repeated heel pain.One pa-tient was diagnosed with Haglund syndrome by CT and musculoskeletal ultrasound,and 1 patient was diagnosed by magnetic resonance imaging(MRI).The symptoms did not improve significantly after corresponding treatment.AS was confirmed after performing relevant examinations including human leukocyte antigen B27,erythrocyte sedimentation rate(ESR),C reactive protein(CRP)test,and CT and MRI of the sacroiliac joint.The misdiagnosis lasted 1 month.After diagnosis,the patient was treated with NSAIDS and biologics.The patient's prognosis was good and follow-up showed stable condition without recur-rence.Conclusion Several AS patients and patients with Haglund syndrome have the same symptoms of Achilles tendon pain,but different accompanying symptoms.Performing relevant examinations including the MRI of the sacroiliac joint,hu-man leukocyte antigen B27,ESR and CRP test can improve the accuracy of early diagnosis and reduce misdiagnosis.