临床误诊误治2024,Vol.37Issue(21) :24-27.DOI:10.3969/j.issn.1002-3429.2024.21.006

系统性红斑狼疮合并水痘患儿误诊及药学监护分析

Analysis of Misdiagnosis and Pharmacological Monitoring of a Child with Systemic Lupus Erythematosus Complicated with Varicella Infection

孟艳 刘福娟 郭敬肖
临床误诊误治2024,Vol.37Issue(21) :24-27.DOI:10.3969/j.issn.1002-3429.2024.21.006

系统性红斑狼疮合并水痘患儿误诊及药学监护分析

Analysis of Misdiagnosis and Pharmacological Monitoring of a Child with Systemic Lupus Erythematosus Complicated with Varicella Infection

孟艳 1刘福娟 2郭敬肖2
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作者信息

  • 1. 050031 石家庄,河北省儿童医院药学部
  • 2. 050031 石家庄,河北省儿童医院肾脏免疫科
  • 折叠

摘要

目的 探讨临床药师参与系统性红斑狼疮(SLE)合并水痘误诊患儿药物治疗方案的价值.方法 分析1 例SLE合并水痘患儿的临床资料.结果 1 例患儿因呕吐、间断低热,误诊为"胃肠炎",给予对症治疗效果不佳.院外误诊时间1 月余.入院后经完善相关检查确诊为SLE、狼疮性肾炎、中度贫血、水痘,给予抗病毒治疗及糖皮质激素冲击治疗,临床药师参与治疗方案的评估与调整、重点关注药物疗效及不良反应的监测等,治疗27d后病情稳定出院.患儿规律门诊随访,病情稳定.结论 实施临床药师药学监护可确保患儿在糖皮质激素冲击治疗期间用药的安全性及有效性,为SLE重症病例提供个体化的药学服务.

Abstract

Objective To investigate the value of clinical pharmacists'participation in drug treatment of misdiagnosed children with systemic lupus erythematosus(SLE)complicated with varicella.Methods The clinical data of 1 SLE child with varicella were analyzed.Results One patient was misdiagnosed as gastroenteritis due to vomiting and intermittent low fe-ver in a local clinic,and the symptomatic treatment was not effective.Out-of-hospital misdiagnosis lasted more than one month.After admission,the patient was diagnosed with SLE,lupus nephritis,moderate anemia,and varicella through rele-vant examination.Antiviral therapy and glucocorticoid shock therapy were given.Clinical pharmacists participated in the eval-uation and adjustment of the treatment plan,with a focus on monitoring the efficacy and adverse reactions.The patient was discharged with stable condition at 27 d after treatment,and received regular outpatient follow-up,and the condition was sta-ble.Conclusion Pharmaceutical monitoring by clinical pharmacists can ensure the safety and effectiveness of glucocorticoid therapy in children,and provide individualized pharmaceutical services for severe SLE patients.

关键词

红斑狼疮,系统性/水痘/误诊/胃肠炎/糖皮质激素类/抗病毒药/药学服务

Key words

Lupus erythematosus,systemic/Chickenpox/Misdiagnosis/Gastroenteritis/Glucocorticoids/Antiviral agents/Pharmaceutical services

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出版年

2024
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
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