临床误诊误治2024,Vol.37Issue(21) :85-90.DOI:10.3969/j.issn.1002-3429.2024.21.016

清热消痈止痛方贴敷联合光子治疗预防剖宫产术后感染的临床效果及安全性分析

Clinical Effect and Safety of Qingre Xiaoyong Zhitong Prescription Com-bined with Photon Therapy in Preventing Abdominal Incision Infection af-ter Cesarean Section

杨彩慧 刘宏 陈艳青 田颖
临床误诊误治2024,Vol.37Issue(21) :85-90.DOI:10.3969/j.issn.1002-3429.2024.21.016

清热消痈止痛方贴敷联合光子治疗预防剖宫产术后感染的临床效果及安全性分析

Clinical Effect and Safety of Qingre Xiaoyong Zhitong Prescription Com-bined with Photon Therapy in Preventing Abdominal Incision Infection af-ter Cesarean Section

杨彩慧 1刘宏 2陈艳青 3田颖1
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作者信息

  • 1. 075000 河北张家口,张家口市妇幼保健院产科
  • 2. 75000 河北张家口,张家口市妇幼保健院分娩中心
  • 3. 075000 河北张家口,张家口市第一医院妇科
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摘要

目的 探讨清热消痈止痛方贴敷联合光子治疗对剖宫产术后感染、切口愈合效果的影响,并分析安全性.方法 选取2022 年1 月至2023 年7 月收治的行剖宫产的患者 150 例,采用随机数字表法分为贴敷组、光子组、联合组各50 例.贴敷组给予清热消痈止痛方贴敷治疗,光子组给予光子治疗,联合组给予清热消痈止痛方贴敷联合光子治疗.对比3 组剖宫产术后感染情况、术后康复进程、术后切口愈合效果、局部微循环指标、血清炎性因子水平[超敏C反应蛋白(hs-CRP)、肿瘤坏死因子-α(TNF-α)、白细胞计数]及切口疼痛评分,记录 3 组不良反应发生情况.结果 3 组腹部浅表切口感染及发热发生率比较差异无统计学意义(P>0.05).联合组切口愈合时间、下床活动时间、住院时间短于贴敷组、光子组,切口愈合良好率高于贴敷组、光子组(P<0.05).术后3d,联合组切口局部毛细血管管径、血流速度高于贴敷组、光子组(P<0.05).术后 1、3d,联合组hs-CRP、TNF-α、白细胞计数低于贴敷组、光子组(P<0.05).联合组术后12h、24h、2d、3d切口疼痛评分低于贴敷组、光子组(P<0.05).3 组不良反应发生率比较差异无统计学意义(P<0.05).结论 清热消痈止痛方贴敷联合光子治疗预防剖宫术后感染效果较好,且不增加不良反应,安全性较高.

Abstract

Objective To investigate the effect of application of Qingre Xiaoyong Zhitong prescription combined with photon therapy on the incidence of infection and wound healing after cesarean section(C-section),and to analyze its safety.Methods A total of 150 patients who underwent C-section from January 2022 to July 2023 were selected and divided into ap-plication group(n=50),photon therapy group(n=50)and combination group(n=50)by random number table method.The application group was treated with Qingre Xiaoyong Zhitong prescription,the photon therapy group was treated with photon therapy,and the combination group was treated with Qingre Xiaoyong Zhitong prescription combined with photon therapy.Postoperative infection,postoperative rehabilitation,postoperative incision healing effect,local microcirculation index,serum inflammatory factor levels[hypersensitive C reactive protein(hs-CRP),tumor necrosis factor-α(TNF-α),white blood cell(WBC)count]and incision pain score of the three groups were compared.The incidence of adverse reactions in the three groups were recorded.Results There was no significant difference in the incidence of superficial abdominal incision infection and fever among the three groups(P>0.05).The wound healing time,time of off-bed activity and length of hospitalization in combination group were shorter than those in application group and photon therapy group,and the rate of good wound healing was higher than that in application group and photon group(P<0.05).At 3 d after operation,the local capillary diameter and blood flow velocity in combination group were higher than those in application group and photon therapy group(P<0.05).At 1 and 3 d after operation,hs-CRP,TNF-α and WBC counts in the combination group were lower than those in the application group and the photon therapy group(P<0.05).Incision pain scores of combination group were lower than those of application group and photon therapy group at 12 h,24 h,2 d and 3 d after operation(P<0.05).There was no significant difference in the incidence of adverse reactions among the three groups(P<0.05).Conclusion The combination of Qingre Xiaoyong Zhitong prescription and photon therapy has a good effect on preventing postoperative infection after cesarean section,and does not increase adverse reactions,with good safety.

关键词

清热消痈止痛方/贴敷/光子治疗/剖宫产术/切口感染/超敏C反应蛋白/肿瘤坏死因子/疼痛测定

Key words

Qingre Xiaoyong Zhitong prescription/Application/Photon therapy/Cesarean section/Incision infec-tion/Hypersensitive C reactive protein/Tumor necrosis factor/Pain measurement

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出版年

2024
临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

CSTPCD
影响因子:0.914
ISSN:1002-3429
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