Objective To investigate the influencing factors of systemic inflammatory response syndrome(SIRS)af-ter flexible ureteroscopy lithotripsy(FURL)for renal calculi,in order to guide preoperative preparation and develop treatment plans,so as to prevent delayed diagnosis and treatment.Methods Ninety-four patients with renal calculi treated from De-cember 2020 to December 2023 were retrospectively selected as the research subjects.All patients received FURL.The inci-dence of SIRS after treatment was statistically analyzed,and accordingly the patients were divided into SIRS group and non-SIRS group.Multivariate logistic regression was used to analyze the risk factors for SIRS in patients with renal calculi after FURL treatment.Results The success rate of one-time examination and stone finding rate of FURL treatment for renal calculi were100.00%(94/94),and the one-time stone clearance rate was94.68%(89/94).After FURL treatment,14 patients had SIRS.The white blood cell(WBC)count was higher in SIRS group than in non-SIRS group,and the proportion patients with albumin/globulin ratio＜1.184,numberofstones≥2,stonesize≥2 cm,preoperativefever,preoperative D-Jtubeim-plantation,systemic inflammatory response index(SIRI)≥0.726 in SIRS group was larger than that in non-SIRS group(P＜0.05).Albumin/globulin ratio＜1.184,WBC count,number of stones≥2,stone size≥2 cm,preoperative fever,preoper-ative D-J tube implantation and SIRI≥0.726 were all independent risk factors for SIRS after FURL treatment in patients with renal calculi(P＜0.05).Conclusion Before FURL treatment,patients with renal calculi should know the risk factors of SIRS in detail,which can guide preoperative preparation and formulate treatment plan,thereby avoiding delayed diagnosis and treatment.
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