Objective To explore the clinical effect of Qinsang Qingre Huatan decoction in acute exacerbation of chronic obstructive pulmonary disease(AECOPD)patients with phlegm-heat stagnation lung syndrome.Methods A total of 150 AECOPD patients with phlegm-heat stagnation lung syndrome admitted from January 2023 to January 2024 were randomly divided into control group(n=75)and observation group(n=75).The control group received conventional Western medi-cine treatment,and the observation group received Qinsang Qingre Huatan decoction combined with conventional Western medicine treatment.The clinical efficacy,airway mucus hypersecretion index and the occurrence of adverse reactions were compared between the two groups,and the traditional Chinese medicine(TCM)syndrome score,pulmonary function,sputum inflammatory factors and the total number of cells before and after treatment were compared between the two groups.Results The total clinical effective rate of the observation group was 92.00%(69/75),which was higher than that of the control group[80.00%(60/75)](P＜0.05).After treatment,the sputum interleukin-8,tumor necrosis factor-α,the total number of cells and various TCM syndrome scores in the observation group were lower than those in the control group,whereas the per-centage of forced expiratory volume in the first second,forced expiratory volume in the first second/forced lung capacity,and forced expiratory volume in the first second in the predicted value were higher than those in the control group(P＜0.05).Af-ter treatment,the scores of sputum color,sputum quality and sputum volume in observation group were lower than those in control group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups during treatment(P＞0.05).Conclusion Qinsang Qingre Huatan decoction can significantly improve the symptoms of AECOPD patients with phlegm-heat stagnation lung syndrome,improve pulmonary function,reduce the inflammatory cells in sputum,and has a significant effect on the improvement of sputum properties,which is an effective adjuvant treatment meth-od,and can enhance the efficacy of conventional Western medicine.
国家科技期刊平台
NSTL
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