Objective To investigate the relationship between the occurrence of syndrome elements,laboratory inde-xes and basic conditions in patients with type 2 diabetes mellitus(T2DM).Methods In total,175 patients with T2DM were selected as subjects for cross-sectional investigation.The distribution of syndrome elements and their combination distribution were analyzed,and baseline data and laboratory indexes were collected.Multivariate Logistic regression was used to analyze their relationship with syndrome elements of T2DM.Results Among the 175 patients,the proportion of Yin deficiency syn-drome was the highest(67.4%),and that of phlegm-dampness syndrome was the highest(65.1%),Yin deficiency syn-drome,phlegm-dampness syndrome,blood stasis syndrome,heat stagnation syndrome and Qi deficiency syndrome accounted for the highest proportion of the top 5 syndrome elements of 16 syndrome elements,while,the bottom 2 syndrome elements with the lowest proportion were syndrome of fluid retention and heat and toxin syndrome.The compound TCM syndrome type were too scattered,and the combination of five syndromes accounted for the highest proportion.According to the combination classification,it was found that the combination was mainly composed of deficiency and solid mixed syndrome,accounting for 84.6%.Age was the influencing factor of blood stasis syndrome,water dampness syndrome and heat stagnation syndrome,while course of disease was the influencing factor of phlegm-heat syndrome,Yang deficiency syndrome and dampness-turbidity syndrome.Blood pressure was the influencing factor of Yin deficiency syndrome,dampness syndrome and phlegm-heat syn-drome,body mass index was the influencing factor of phlegm-dampness syndrome and water-dampness syndrome,and gender was the influencing factor of Qi deficiency syndrome and blood deficiency syndrome.Free triiodothyrine was the influencing factor of Yin deficiency and Qi deficiency syndrome,free thyroxine was the influencing factor of stagnation heat syndrome and blood deficiency syndrome,thyrotropin was the influencing factor of Yang deficiency syndrome and blood stasis syndrome,anti-thyroglobulin antibody was the influencing factor of stagnation heat syndrome and liver-Yang syndrome,and thyrotropin re-ceptor antibody was the influencing factor of phlegm-heat syndrome and phlegm-dampness syndrome.C-peptide was the influ-encing factor of Yin deficiency syndrome,blood stasis syndrome and dampness syndrome,insulin was the influencing factor of Qi deficiency syndrome,and glycated hemoglobin was the influencing factor of dampness syndrome.Conclusion Yin defi-ciency syndrome,phlegm-dampness syndrome,blood stasis syndrome,heat stagnation syndrome and Qi deficiency syndrome are the main syndromes in T2DM patients,but the complex TCM syndrome types are mainly characterized by a combination of deficiency and excess syndrome.Different syndrome types have obvious relationship with glucose metabolism index,basic con-dition and thyroid function.