首页|隐匿性听力损失发病机制和诊断方法研究进展

隐匿性听力损失发病机制和诊断方法研究进展

Research Progress on Pathogenesis and Diagnosis of Hidden Hearing Loss

扫码查看
隐匿性听力损失以纯音测听结果正常,但伴有严重噪声环境下言语识别功能障碍为特点.目前,有1%~10%的听阈正常人群有隐匿性听力损失的症状表现.与其他类型的感音神经性听力损失不同,隐匿性听力损失的病理损伤不伴有毛细胞死亡或丢失,而以毛细胞和螺旋神经节细胞间带状突触丢失为主要表现.早期患有隐匿性听力损失的患者未来更易产生老年性听力损失,对耳毒性药物和噪声的耐受性也会发生显著下降.因此,为了更好应对隐匿性听力损失带来的影响,本文就隐匿性听力损失发病机制和诊断方法的研究进展做一综述.
Objective Hidden hearing loss(HHL)is characterized by normal pure tone audiometry but severe speech recognition impairment in noisy environments.Currently,approximately 1%-10%of people with normal hearing thresholds have symptoms of HHL.Unlike other types of sensorineural hearing loss,the pathological damage of HHL doesn't involve the death or loss of hair cells,but is mainly manifested by the reduction of the ribbon synapses between hair cells and spiral ganglion neuron cells.Patients with early HHL are more likely to develop age-related hearing loss in the future,and their tolerance to ototoxic drugs and noise will decrease significantly.Therefore,this review summarizes the research progress on the pathogenesis and diagnosis of HHL to better cope with its impact on the population.

Hidden hearing lossRibbon synapsesInducing factorsPathogenesisDiagnostic methodsReview

郑泽宇、夏黎红、付洋、姜一弘、朱靖、畅通、张敏、阮柏、王小成

展开 >

710032 西安,空军军医大学航空航天医学系航空航天临床医学中心航空航天医学教育部重点实验室

710032 西安,空军军医大学西京医院空勤科

710032 西安,空军军医大学基础医学院

隐匿性听力损失 带状突触 诱发因素 发病机制 诊断方法 综述

2025

临床误诊误治
解放军白求恩国际和平医院

临床误诊误治

影响因子:0.914
ISSN:1002-3429
年,卷(期):2025.38(2)