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中国变异型心绞痛临床研究面临机遇与挑战

Clinical observational research on variant angina pectoris in China faces opportunities and challenges

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由冠状动脉(冠脉)严重痉挛(功能性闭塞)引起的变异型心绞痛(variant angina pectoris,VAP)在中国相当常见.由于理论认识不足和临床诊治经验不够丰富,致使漏诊、误诊甚至误治的情况时有发生.本文就VAP有关基本概念、基础理论、冠脉痉挛药物激发试验、VAP诊断标准、VAP与相关心血管疾病重大事件(急性心肌梗死、梗死后心绞痛、冠脉介入后自发性心绞痛、晕厥、心脏骤停及猝死等)的关系及VAP临床分型的价值等进行阐述,有助于解决临床工作中的实际问题,提高VAP的诊治水平,进一步推动对VAP的深入临床研究.
Variant angina pectoris(VAP)caused by severe spasm(functional occlusion)of the coronary artery is common in China.Due to lack of theoretical understanding and experience in clinical diagnosis and treatment,missed diagnosis,misdiagnosis and even mistreatment often occur.In this article,the basic concepts and theories of VAP,coronary spasm drug stimulation test,VAP diagnostic criteria,the relationship between VAP and major cardiovascular disease events(acute myocardial infarction,post-infarction angina pectoris,spontaneous angina pec-toris after coronary intervention,syncope,cardiac arrest and sudden death,etc.)and the value of VAP clinical classification are expounded.It is helpful to solve the practical problems in clinical work,improve the level of di-agnosis and treatment in VAP,and further promote the clinical research of VAP.

variant angina pectorisacute myocardial infarctionpercutaneous coronary interventionvariant angina pectoris syncopevariant angina pectoris sudden death

沈玉祥

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阜外华中心血管病医院河南省人民医院心脏中心郑州大学人民医院心内科(郑州,450003)

变异型心绞痛 急性心肌梗死 经皮冠状动脉介入术 变异型心绞痛晕厥 变异型心绞痛猝死

河南医学科技攻关项目中国临床试验注册中心

2006-0131ChiCTR1800018394

2024

10.13201/j.issn.1001-1439.2024.02.002

临床心血管病杂志
华中科技大学心血管病研究所 华中科技大学协和医院

临床心血管病杂志

CSTPCD
影响因子：0.653
ISSN：1001-1439
年,卷(期)：2024.40(2)
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