Although the treatments of mitral valve diseases by traditional surgery are well developed,severe trauma,extracorporeal circulation,and intraoperative myocardial-ischemia reperfusion injury cause the failure of elderly and high-risk patients to receive surgical treatments.In recent years,the thriving development of tran-scatheter mitral valve replacement(TMVR)has brought hope to such patients.TMVR can be performed by mini-mally invasive intervention.Nowadays,a variety of mitral interventional valves are currently in extensive clinical trials.The safety and efficacy of prosthetic valves are optimistic.The initial results of relevant studies are posi-tive.However,there are still many problems and challenges with TMVR.This article reviews the research pro-gress and application status of TMVR.
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