经导管二尖瓣置换术的研究进展
Research process on transcatheter mitral valve replacement
李健 1贾若雪 2梅波3
作者信息
- 1. 达州市中心医院心脏血管外科(四川达州,635000);川北医学院临床医学院·附属医院(临床医学系)
- 2. 川北医学院医学影像学院
- 3. 达州市中心医院心脏血管外科(四川达州,635000)
- 折叠
摘要
尽管传统外科手术对二尖瓣疾病的治疗已非常成熟,但手术创伤较大、体外循环以及术中心肌缺血再灌注损伤等因素导致高龄高风险患者无法耐受.近年来,经导管二尖瓣置换术(transcatheter mitral valve re-placement,TMVR)的积极发展让这类患者迎来曙光.TMVR通过微创介入途径即可完成手术治疗.目前,已有多种二尖瓣介入瓣膜进入大范围临床试验阶段,相关研究的初期结果良好,瓣膜安全性和有效性相对乐观,但TMVR仍面临诸多困难和挑战.本文就TMVR的研究进展和应用现状进行综述.
Abstract
Although the treatments of mitral valve diseases by traditional surgery are well developed,severe trauma,extracorporeal circulation,and intraoperative myocardial-ischemia reperfusion injury cause the failure of elderly and high-risk patients to receive surgical treatments.In recent years,the thriving development of tran-scatheter mitral valve replacement(TMVR)has brought hope to such patients.TMVR can be performed by mini-mally invasive intervention.Nowadays,a variety of mitral interventional valves are currently in extensive clinical trials.The safety and efficacy of prosthetic valves are optimistic.The initial results of relevant studies are posi-tive.However,there are still many problems and challenges with TMVR.This article reviews the research pro-gress and application status of TMVR.
关键词
经导管二尖瓣置换术/介入治疗/人工瓣膜Key words
transcatheter mitral valve replacement/interventional therapy/prosthetic valve引用本文复制引用
基金项目
四川省科技厅应用基础项目(2021YJ0208)
出版年
2024
NETL
NSTL
万方数据