首页|免疫检查点抑制剂相关心肌炎诊疗进展

免疫检查点抑制剂相关心肌炎诊疗进展

Advances in the management of immune checkpoint inhibitor-associated myocarditis

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免疫检查点抑制剂(immune checkpoint inhibitor,ICI)是肿瘤治疗的一大突破,在临床应用日益广泛.ICI相关心肌炎是ICI药物的罕见不良反应之一,病死率较高.尽管国内外均报道了该不良反应的治疗经验和指南,但部分医生在临床工作中仍存在认知不足、监管评估方案缺乏等问题.故本文对ICI相关心肌炎发病机制、诊断、治疗策略进行综述,以提高肿瘤科及心脏科医师的认识.
Immune checkpoint inhibitors(ICI)are a major breakthrough in oncology treatment and are in-creasingly used in clinical practice.ICI-associated myocarditis is one of the rare adverse reactions to ICI drugs,with a high mortality rate.Guidelines for treating this adverse reaction have been written both domestically and in-ternationally at home and abroad.However,there is still a lack of awareness and reliable regulatory assessment protocols in clinical work.Therefore,this article reviews the pathogenesis,diagnosis,and treatment strategies of ICI-associated myocarditis in order to raise the awareness of oncologists and cardiologists.

myocarditisimmune checkpoint inhibitor

李泞甫、李智可、陈旭澜、皈燕

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川北医学院附属医院肿瘤科(四川南充,637000)

川北医学院临床医学系

心肌炎 免疫检查点抑制剂

国家自然科学基金南充市市校合作科研专项南充市市校合作科研专项

20SXQT032920SXQT025420SXQT0071

2024

临床心血管病杂志
华中科技大学心血管病研究所 华中科技大学协和医院

临床心血管病杂志

CSTPCD
影响因子:0.653
ISSN:1001-1439
年,卷(期):2024.40(3)
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