Objective:To investigate the relationship between BMI and prognosis of chronic heart failure.Methods:We retrospectively analyzed clinical data of 315 patients hospitalized with chronic heart failure in Beijing Friendship Hospital Affiliated with Capital Medical University from May 2015 to June 2020,patients were fol-lowed up for 2 years.According to BMI,patients were divided into the under-weight group(BMI≤18.5 kg/m2,n=14),normal-weight group(18.5 kg/m2＜BMI＜25 kg/m2,n=137),over-weight group(25 kg/m2≤BMI＜30 kg/m2,n=115),obese group(30 kg/m2≤BMI＜35 kg/m2,n=34),and severe-obese group(BMI≥35 kg/m2,n=15).Baselinedata were compared among the five groups.Logistic regression was used to analyze the relation-ship between all-cause mortality,cardiac death,and BMI.Results:The 2-year follow-up results showed that the all-cause mortality rates in the under-weight weight,normal-weight,over-weight,obese,and severe-obese groups were 50％,32.1％,13％,5.9％,and 6.7％,respectively,and the rate in the over-weight and obese groups was significantly lower than that in the normal-weight group(P＜0.001),but in the severe-obese group was higher than that in the obese group.The cardiac mortality rates in the 5 groups were 35.7％,27.7％,10.4％,5.9％,and 0,respectively,the rate gradually decreased as BMI increased(P＜0.001).After multiple factor adjustment,the results of logistic regression analysis showed that over-weight and obese were independent prognostic factors for patients with chronic heart failure.Conclusion:BMI can be used to assess the prognosis of patients with heart failure,and the lower BMI is an independent risk factor for the 2-year prognosis of patients with chronic heart fail-ure.BMI conforms to the obesity paradox in a certain range,but severe obese can lead to an increase in all-cause mortality in patients with heart failure.
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