Objective:To analyze risk factors predicting periprocedural myocardial injury in coronary heart dis-ease patients undergoing elective PCI,and subsequently establish and validate a nomogram prediction model.Methods:A total of 428 coronary heart disease patients who underwent elective PCI at the First People's Hospital of Lianyungang and the First Hospital of Nanjing from January 2017 to December 2021 were enrolled as study subjects.The endpoint event was periprocedural myocardial injury,defined as the peak value of cardiac troponin exceeding the normal value by more than 5 times within 24 hours after PCI.Patients were divided into the peripro-cedural myocardial injury group(n=207)and the non-periprocedural myocardial injury group(n-221).Multiva-riate logistic analysis was employed to explore the risk factors affectingthe occurrence of periprocedural myocardi-al injury,and a nomogram model was constructed and validated.Results:Patients in the periprocedural myocardi-al injury group were older and had more stents implanted,larger lipid plaque volume,and smaller minimum lu-men area compared to the non-periprocedural myocardial injury group(all P＜0.05).Multivariate logistic regres-sion analysis showed that age(OR=1.039,95％CI:1.015-1.064,P=0.001),number of stents(OR=1.792,95％CI:1.285-2.499,P=0.001),minimum lumen area(OR=0.747,95％CI:0.580-0.962,P=0.024),and lipid plaque volume(OR=1.007,95％CI:1.000-1.014,P=0.049)were risk factors for periprocedural myocar-dial injury.Based on the results of logistic regression analysis,a nomogram model was constructed,which the ar-ea under the ROC(AUC)was 0.711 for predicting periprocedural myocardial injury.The calibration curve showed that the incidence of periprocedural myocardial injury in the modeling and validation groups was basically consistent with the actual incidence.Conclusion:Age,stent numbers,minimum lumen area,and lipid plaque vol-ume are independent risk factors for periprocedural myocardial injury.The nomogram model based on these four factors demonstrates good prediction efficiency and consistency,providing an effective tool for clinical decision-making in patients undergoing elective PCI.
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