The application value of platelet/lymphocyte ratio,fibrinogen/albumin ratio in the prognosis evaluation of patients with myocardial infarction with non-obstructive coronary arteries
Objective:The aim of this study was to evaluate the prognostic value of platelet/lymphocyte ratio(PLR),fibrinogen/albumin ratio(FAR)and their combination in patients with myocardial infarction with non-ob-structive coronary arteries(MINOCA).Methods:The clinical data of 438 patients diagnosed with MINOCA in Cangzhou People's Hospital from May 2018 to December 2022 were retrospectively collected.Patients were divid-ed into MACCE group(n=116)and non-MACCE group(n=322)according to whether major adverse cardiovas-cular and cerebrovascular events(MACCE)occurred during follow-up.Logistic regression was used to analyze the prognostic factors of MINOCA patients.ROC curve was used to evaluate the predictive value of PLR,FAR and their combination for MACCE during follow-up.Results:There were significant differences in the proportion of diabetes,lymphocytes,neutrophils,albumin,high-density lipoprotein cholesterol,uric acid,left ventricular ejec-tion fraction,PLR and FAR between the two groups(all P＜0.05).Multivariate logistic regression analysis showed that diabetes,neutrophils,uric acid,left ventricular ejection fraction,PLR and FAR were independent in-fluencing factors of MACCE in MINOCA patients.The area under the ROC curve(AUC)of PLR,FAR and their combination in predicting MACCE was 0.656,0.691 and 0.762,respectively.Conclusion:High PLR and high FAR are associated with an increased risk of MACCE in MINOCA patients,which may help to improve the clini-cal management strategy of MINOCA patients.
myocardial infarction with non-obstructive coronary arteriesplatelet/lymphocyte ratiofibrino-gen/albumin ratiomajor adverse cardiac and cerebrovascular eventscorrelation
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